Hashimoto's thyroiditis

Hiroshi E. Takami, Rika Miyabe, Kaori Kameyama

Research output: Contribution to journalReview article

21 Citations (Scopus)

Abstract

Goiters were often associated with iodine deficiency in European mountain areas, with some goiters being quite disfiguring. However, some goiters seem not to be related to iodine deficiency. One of the types of goiter that are unrelated to iodine deficiency is the disease described by Hakaru Hashimoto in 1912. Hashimoto described it as a special characteristic of a new type of lymphomatous thyroid tumor in Japan, and this entity was recognized as an autoimmune disease of the thyroid many years later. Hashimoto published his article in a German journal because that was the scientific language of the time, and he thought that writing in German would make the work more widely available around the world. Patients with Hashimoto's thyroiditis are usually asymptomatic, and some patients develop goiters with or without hypothyroidism. The goiters and hypothyroidism usually respond to treatment with thyroid hormone. The dose of thyroid hormone must be carefully titrated because there may be autonomous thyroid function resulting from thyroid-stimulating antibodies despite the hypothyroid state.

Original languageEnglish
Pages (from-to)688-692
Number of pages5
JournalWorld Journal of Surgery
Volume32
Issue number5
DOIs
Publication statusPublished - 2008 May 1

ASJC Scopus subject areas

  • Surgery

Fingerprint Dive into the research topics of 'Hashimoto's thyroiditis'. Together they form a unique fingerprint.

  • Cite this

    Takami, H. E., Miyabe, R., & Kameyama, K. (2008). Hashimoto's thyroiditis. World Journal of Surgery, 32(5), 688-692. https://doi.org/10.1007/s00268-008-9485-0