Haterumaimides A-E, five new dichlorolissoclimide-type diterpenoids from an ascidian, Lissoclinum sp.

Md Jasim Uddin, Susumu Kokubo, Kiyotake Suenaga, Katsuhiro Ueda, Daisuke Uemura

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Five new dichlorolissoclimide-type diterpenoids, haterumaimides A-E, were isolated from an ascidian, Lissoclinum sp., and the absolute stereostructures of haterumaimides A-D and the relative stereostructure of haterumaimide E were determined by spectroscopic and chemical analyses. Haterumaimides A-E inhibited the first cleavage of fertilized sea urchin eggs and exhibited cytotoxicity against P388 cells.

Original languageEnglish
Pages (from-to)1039-1047
Number of pages9
JournalHeterocycles
Volume54
Issue number2
Publication statusPublished - 2001 Feb 1
Externally publishedYes

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Urochordata
Sea Urchins
Diterpenes
Cytotoxicity
Eggs
dichlorolissoclimide

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Haterumaimides A-E, five new dichlorolissoclimide-type diterpenoids from an ascidian, Lissoclinum sp. / Uddin, Md Jasim; Kokubo, Susumu; Suenaga, Kiyotake; Ueda, Katsuhiro; Uemura, Daisuke.

In: Heterocycles, Vol. 54, No. 2, 01.02.2001, p. 1039-1047.

Research output: Contribution to journalArticle

Uddin, MJ, Kokubo, S, Suenaga, K, Ueda, K & Uemura, D 2001, 'Haterumaimides A-E, five new dichlorolissoclimide-type diterpenoids from an ascidian, Lissoclinum sp.', Heterocycles, vol. 54, no. 2, pp. 1039-1047.
Uddin, Md Jasim ; Kokubo, Susumu ; Suenaga, Kiyotake ; Ueda, Katsuhiro ; Uemura, Daisuke. / Haterumaimides A-E, five new dichlorolissoclimide-type diterpenoids from an ascidian, Lissoclinum sp. In: Heterocycles. 2001 ; Vol. 54, No. 2. pp. 1039-1047.
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