Heat dissipation characteristics of magnetite nanoparticles and their application to macrophage cells

Ryo Kasuya; Teppei Kikuchi; Hiroaki Mamiya; Koji Ioku; Shota Endo; Akira Nakamura; Toshiyuki Takai; Jeyadevan Balachandran

doi:10.1016/j.phpro.2010.11.042

Heat dissipation characteristics of magnetite nanoparticles and their application to macrophage cells

Ryo Kasuya, Teppei Kikuchi, Hiroaki Mamiya, Koji Ioku, Shota Endo, Akira Nakamura, Toshiyuki Takai, Jeyadevan Balachandran

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

We report the results of the study undertaken to determine relative contributions of Néel and Brownian relaxations on magnetic heat dissipation by investigating the physical, magnetic and heating characteristics of magnetite suspension dispersing particles ranging in average diameter from 10.0 to 15.7 nm. Heating characteristics depended on the primary particle size and the viscosity of the medium. In the case of the sample with average diameter of 12.5 nm, the effective specific absorption rate dropped by 27 % (22.9×10^-9 to 16.8×10^-9 Wg^-1Oe ^-2Hz^-1). In contrast, the decrease of 67 % (29.5×10^-9 to 9.7×10^-9 Wg^-1Oe ^-2Hz^-1) was observed for the sample with average diameter of 15.7 nm. The potential of these particles as thermal seeds was tested by feeding the macrophage and exposing them to an alternative current magnetic field strength and frequency of 40 Oe and 600 kHz, respectively. The uptake of magnetite particles by the macrophage was adequate to raise the temperature of cell suspension by 8°C required for thermal necrosis.

Original language	English
Pages (from-to)	186-189
Number of pages	4
Journal	Physics Procedia
Volume	9
DOIs	https://doi.org/10.1016/j.phpro.2010.11.042
Publication status	Published - 2010
Externally published	Yes

Keywords

Hyperthermia
Macrophage
Magnetite
Nanobiotechnology

ASJC Scopus subject areas

Physics and Astronomy(all)

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10.1016/j.phpro.2010.11.042

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title = "Heat dissipation characteristics of magnetite nanoparticles and their application to macrophage cells",

abstract = "We report the results of the study undertaken to determine relative contributions of N{\'e}el and Brownian relaxations on magnetic heat dissipation by investigating the physical, magnetic and heating characteristics of magnetite suspension dispersing particles ranging in average diameter from 10.0 to 15.7 nm. Heating characteristics depended on the primary particle size and the viscosity of the medium. In the case of the sample with average diameter of 12.5 nm, the effective specific absorption rate dropped by 27 % (22.9×10-9 to 16.8×10-9 Wg-1Oe -2Hz-1). In contrast, the decrease of 67 % (29.5×10-9 to 9.7×10-9 Wg-1Oe -2Hz-1) was observed for the sample with average diameter of 15.7 nm. The potential of these particles as thermal seeds was tested by feeding the macrophage and exposing them to an alternative current magnetic field strength and frequency of 40 Oe and 600 kHz, respectively. The uptake of magnetite particles by the macrophage was adequate to raise the temperature of cell suspension by 8°C required for thermal necrosis.",

keywords = "Hyperthermia, Macrophage, Magnetite, Nanobiotechnology",

author = "Ryo Kasuya and Teppei Kikuchi and Hiroaki Mamiya and Koji Ioku and Shota Endo and Akira Nakamura and Toshiyuki Takai and Jeyadevan Balachandran",

note = "Funding Information: This work was supported by Grant-in-Aid for Young Scientists (A) #21680038.",

year = "2010",

doi = "10.1016/j.phpro.2010.11.042",

language = "English",

volume = "9",

pages = "186--189",

journal = "Physics Procedia",

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T1 - Heat dissipation characteristics of magnetite nanoparticles and their application to macrophage cells

AU - Kasuya, Ryo

AU - Kikuchi, Teppei

AU - Mamiya, Hiroaki

AU - Ioku, Koji

AU - Endo, Shota

AU - Nakamura, Akira

AU - Takai, Toshiyuki

AU - Balachandran, Jeyadevan

N1 - Funding Information: This work was supported by Grant-in-Aid for Young Scientists (A) #21680038.

PY - 2010

Y1 - 2010

N2 - We report the results of the study undertaken to determine relative contributions of Néel and Brownian relaxations on magnetic heat dissipation by investigating the physical, magnetic and heating characteristics of magnetite suspension dispersing particles ranging in average diameter from 10.0 to 15.7 nm. Heating characteristics depended on the primary particle size and the viscosity of the medium. In the case of the sample with average diameter of 12.5 nm, the effective specific absorption rate dropped by 27 % (22.9×10-9 to 16.8×10-9 Wg-1Oe -2Hz-1). In contrast, the decrease of 67 % (29.5×10-9 to 9.7×10-9 Wg-1Oe -2Hz-1) was observed for the sample with average diameter of 15.7 nm. The potential of these particles as thermal seeds was tested by feeding the macrophage and exposing them to an alternative current magnetic field strength and frequency of 40 Oe and 600 kHz, respectively. The uptake of magnetite particles by the macrophage was adequate to raise the temperature of cell suspension by 8°C required for thermal necrosis.

AB - We report the results of the study undertaken to determine relative contributions of Néel and Brownian relaxations on magnetic heat dissipation by investigating the physical, magnetic and heating characteristics of magnetite suspension dispersing particles ranging in average diameter from 10.0 to 15.7 nm. Heating characteristics depended on the primary particle size and the viscosity of the medium. In the case of the sample with average diameter of 12.5 nm, the effective specific absorption rate dropped by 27 % (22.9×10-9 to 16.8×10-9 Wg-1Oe -2Hz-1). In contrast, the decrease of 67 % (29.5×10-9 to 9.7×10-9 Wg-1Oe -2Hz-1) was observed for the sample with average diameter of 15.7 nm. The potential of these particles as thermal seeds was tested by feeding the macrophage and exposing them to an alternative current magnetic field strength and frequency of 40 Oe and 600 kHz, respectively. The uptake of magnetite particles by the macrophage was adequate to raise the temperature of cell suspension by 8°C required for thermal necrosis.

KW - Hyperthermia

KW - Macrophage

KW - Magnetite

KW - Nanobiotechnology

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JO - Physics Procedia

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ER -

Heat dissipation characteristics of magnetite nanoparticles and their application to macrophage cells

Abstract

Keywords

ASJC Scopus subject areas

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