Hepatobiliary tumor organoids for personalized medicine: a multicenter view on establishment, limitations, and future directions

Gilles S. van Tienderen, Ling Li, Laura Broutier, Yoshimasa Saito, Patricia Inacio, Meritxell Huch, Florin M. Selaru, Luc J.W. van der Laan, Monique M.A. Verstegen

Research output: Contribution to journalComment/debatepeer-review

3 Citations (Scopus)

Abstract

Reliable establishment of tumor organoids is paramount to advance applications of organoid technology for personalized medicine. Here, we share our multi-center experience on initiation and tumorigenic confirmation of hepatobiliary cancer organoids. We discuss current concerns, propose potential solutions, and provide future perspectives for improvements in hepatobiliary cancer organoid establishment.

Original languageEnglish
Pages (from-to)226-230
Number of pages5
JournalCancer Cell
Volume40
Issue number3
DOIs
Publication statusPublished - 2022 Mar 14

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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