@article{e030f7439b4a4080bf3be28e4db295dd,
title = "Hexamollamide, a hexapeptide from an Okinawan ascidian Didemnum molle",
abstract = "The bioassay-guided fractionation of the cytotoxic constituents of the Okinawan ascidian Didemnum molle led to the isolation of hexamollamide (1), a hexapeptide. The gross structure and relative stereostructure of 1 were established by spectroscopic analysis including 2D NMR techniques and single-crystal X-ray diffraction analysis. The absolute stereostructure was determined by chiral HPLC analysis of acid hydrolysates of 1. Hexamollamide (1) exhibits moderate cytotoxicity against HeLa S3 cells.",
author = "Toshiaki Teruya and Hiroaki Sasaki and Kiyotake Suenaga",
note = "Funding Information: We would like to thank Professors Akira Sekiguchi and Masaaki Ichinohe (Univ. of Tsukuba) for the measurement of X-ray crystallographic analysis and helpful discussion. We would like to thank Professor Hideo Kigoshi (Univ. of Tsukuba) for performing the ESIMS analysis. This work was supported by Grant-in-Aid for Young Scientists (B), Keio Leading-edge Laboratory of Science and Technology, Keio Gijuku Academic Development Funds, The Japan Securities Scholarship Foundation. Copyright: Copyright 2008 Elsevier B.V., All rights reserved.",
year = "2008",
month = sep,
day = "1",
doi = "10.1016/j.tetlet.2008.06.086",
language = "English",
volume = "49",
pages = "5297--5299",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Limited",
number = "36",
}