Hibernoma Showing High Uniform Accumulation on an 18F-Fluorodeoxyglucose Positron Emission Tomography Scan

A Case Report

Yasuhiro Kamata, Kazutaka Kikuta, Michiro Susa, Kazumasa Nishimoto, Aya Sasaki, Kaori Kameyama, Koji Murakami, Masaya Nakamura, Morio Matsumoto, Hideo Morioka

Research output: Contribution to journalArticle

Abstract

Background: Hibernoma is a rare, benign, soft tissue tumor arising from brown fat that cannot be distinguished from other lipogenic tumors on computed tomography and magnetic resonance imaging (MRI) scans. On the other hand, the image of hibernoma on 18F-fluorodeoxyglucose positron emission tomography (18F-FDG-PET) is different from that of other lipogenic tumors. However, fewer studies have investigated the typical features of hibernoma on PET scans. We present the case of a hibernoma that was incidentally detected on 18F-FDG-PET. Case Presentation: A 48-year-old Asian man underwent 18F-FDG-PET for routine follow-up of gastric cancer. The patient reported a painless soft mass on the upper arm that had persisted for several years. On 18F-FDG-PET, the mass showed a maximum standardized uptake value of 9.6. The mass showed high intensity on T1- and T2-weighted MRI scans, and showed focally enhanced septa after gadolinium administration. The mass was surgically resected. Histopathologically, the mass was composed of brown adipose cells characteristic of hibernoma. His postoperative course was uneventful, and there was no local recurrence at the final 24-month follow-up. Conclusion: Hibernoma showed strong uniform accumulation on 18F-FDG-PET, suggesting that 18F-FDG-PET would be a useful modality for the differential diagnosis of hibernoma versus other lipogenic tumors.

Original languageEnglish
Pages (from-to)427-431
Number of pages5
JournalCase Reports in Oncology
Volume9
Issue number2
DOIs
Publication statusPublished - 2016

Fingerprint

Lipoma
Fluorodeoxyglucose F18
Positron-Emission Tomography
Neoplasms
Magnetic Resonance Imaging
Brown Adipose Tissue
Gadolinium
Stomach Neoplasms
Arm
Differential Diagnosis
Tomography
Recurrence

Keywords

  • F-FDG-PET
  • Brown fat
  • Hibernoma

ASJC Scopus subject areas

  • Oncology

Cite this

Hibernoma Showing High Uniform Accumulation on an 18F-Fluorodeoxyglucose Positron Emission Tomography Scan : A Case Report. / Kamata, Yasuhiro; Kikuta, Kazutaka; Susa, Michiro; Nishimoto, Kazumasa; Sasaki, Aya; Kameyama, Kaori; Murakami, Koji; Nakamura, Masaya; Matsumoto, Morio; Morioka, Hideo.

In: Case Reports in Oncology, Vol. 9, No. 2, 2016, p. 427-431.

Research output: Contribution to journalArticle

Kamata, Yasuhiro ; Kikuta, Kazutaka ; Susa, Michiro ; Nishimoto, Kazumasa ; Sasaki, Aya ; Kameyama, Kaori ; Murakami, Koji ; Nakamura, Masaya ; Matsumoto, Morio ; Morioka, Hideo. / Hibernoma Showing High Uniform Accumulation on an 18F-Fluorodeoxyglucose Positron Emission Tomography Scan : A Case Report. In: Case Reports in Oncology. 2016 ; Vol. 9, No. 2. pp. 427-431.
@article{01c8ce55b92e4a7084c03b7756ed61b6,
title = "Hibernoma Showing High Uniform Accumulation on an 18F-Fluorodeoxyglucose Positron Emission Tomography Scan: A Case Report",
abstract = "Background: Hibernoma is a rare, benign, soft tissue tumor arising from brown fat that cannot be distinguished from other lipogenic tumors on computed tomography and magnetic resonance imaging (MRI) scans. On the other hand, the image of hibernoma on 18F-fluorodeoxyglucose positron emission tomography (18F-FDG-PET) is different from that of other lipogenic tumors. However, fewer studies have investigated the typical features of hibernoma on PET scans. We present the case of a hibernoma that was incidentally detected on 18F-FDG-PET. Case Presentation: A 48-year-old Asian man underwent 18F-FDG-PET for routine follow-up of gastric cancer. The patient reported a painless soft mass on the upper arm that had persisted for several years. On 18F-FDG-PET, the mass showed a maximum standardized uptake value of 9.6. The mass showed high intensity on T1- and T2-weighted MRI scans, and showed focally enhanced septa after gadolinium administration. The mass was surgically resected. Histopathologically, the mass was composed of brown adipose cells characteristic of hibernoma. His postoperative course was uneventful, and there was no local recurrence at the final 24-month follow-up. Conclusion: Hibernoma showed strong uniform accumulation on 18F-FDG-PET, suggesting that 18F-FDG-PET would be a useful modality for the differential diagnosis of hibernoma versus other lipogenic tumors.",
keywords = "F-FDG-PET, Brown fat, Hibernoma",
author = "Yasuhiro Kamata and Kazutaka Kikuta and Michiro Susa and Kazumasa Nishimoto and Aya Sasaki and Kaori Kameyama and Koji Murakami and Masaya Nakamura and Morio Matsumoto and Hideo Morioka",
year = "2016",
doi = "10.1159/000448240",
language = "English",
volume = "9",
pages = "427--431",
journal = "Case Reports in Oncology",
issn = "1662-6575",
number = "2",

}

TY - JOUR

T1 - Hibernoma Showing High Uniform Accumulation on an 18F-Fluorodeoxyglucose Positron Emission Tomography Scan

T2 - A Case Report

AU - Kamata, Yasuhiro

AU - Kikuta, Kazutaka

AU - Susa, Michiro

AU - Nishimoto, Kazumasa

AU - Sasaki, Aya

AU - Kameyama, Kaori

AU - Murakami, Koji

AU - Nakamura, Masaya

AU - Matsumoto, Morio

AU - Morioka, Hideo

PY - 2016

Y1 - 2016

N2 - Background: Hibernoma is a rare, benign, soft tissue tumor arising from brown fat that cannot be distinguished from other lipogenic tumors on computed tomography and magnetic resonance imaging (MRI) scans. On the other hand, the image of hibernoma on 18F-fluorodeoxyglucose positron emission tomography (18F-FDG-PET) is different from that of other lipogenic tumors. However, fewer studies have investigated the typical features of hibernoma on PET scans. We present the case of a hibernoma that was incidentally detected on 18F-FDG-PET. Case Presentation: A 48-year-old Asian man underwent 18F-FDG-PET for routine follow-up of gastric cancer. The patient reported a painless soft mass on the upper arm that had persisted for several years. On 18F-FDG-PET, the mass showed a maximum standardized uptake value of 9.6. The mass showed high intensity on T1- and T2-weighted MRI scans, and showed focally enhanced septa after gadolinium administration. The mass was surgically resected. Histopathologically, the mass was composed of brown adipose cells characteristic of hibernoma. His postoperative course was uneventful, and there was no local recurrence at the final 24-month follow-up. Conclusion: Hibernoma showed strong uniform accumulation on 18F-FDG-PET, suggesting that 18F-FDG-PET would be a useful modality for the differential diagnosis of hibernoma versus other lipogenic tumors.

AB - Background: Hibernoma is a rare, benign, soft tissue tumor arising from brown fat that cannot be distinguished from other lipogenic tumors on computed tomography and magnetic resonance imaging (MRI) scans. On the other hand, the image of hibernoma on 18F-fluorodeoxyglucose positron emission tomography (18F-FDG-PET) is different from that of other lipogenic tumors. However, fewer studies have investigated the typical features of hibernoma on PET scans. We present the case of a hibernoma that was incidentally detected on 18F-FDG-PET. Case Presentation: A 48-year-old Asian man underwent 18F-FDG-PET for routine follow-up of gastric cancer. The patient reported a painless soft mass on the upper arm that had persisted for several years. On 18F-FDG-PET, the mass showed a maximum standardized uptake value of 9.6. The mass showed high intensity on T1- and T2-weighted MRI scans, and showed focally enhanced septa after gadolinium administration. The mass was surgically resected. Histopathologically, the mass was composed of brown adipose cells characteristic of hibernoma. His postoperative course was uneventful, and there was no local recurrence at the final 24-month follow-up. Conclusion: Hibernoma showed strong uniform accumulation on 18F-FDG-PET, suggesting that 18F-FDG-PET would be a useful modality for the differential diagnosis of hibernoma versus other lipogenic tumors.

KW - F-FDG-PET

KW - Brown fat

KW - Hibernoma

UR - http://www.scopus.com/inward/record.url?scp=84986880406&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84986880406&partnerID=8YFLogxK

U2 - 10.1159/000448240

DO - 10.1159/000448240

M3 - Article

VL - 9

SP - 427

EP - 431

JO - Case Reports in Oncology

JF - Case Reports in Oncology

SN - 1662-6575

IS - 2

ER -