High dose rate intracavitary brachytherapy for recurrent cervical cancer of the vaginal stump following hysterectomy

Hisao Ito, Hideo Kumagaya, Naoyuki Shigematsu, Iku Nishiguchi, Toshitake Nakayama, Shozo Hashimoto

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Forty-eight patients with recurrent cervical cancer of the vaginal stump following hysterectomy for cervical cancer, were treated with high dose rate intracavitary brachytherapy with or without external irradiation. The intervals between primary surgery and vaginal recurrences varied widely from 3 months to 36 years. Patients were classified into two groups, either with or without palpable tumor of the vaginal stump. Tumor size was determined by bimanual rectovaginal examination at the time of recurrence. Survival rates were 8% for the group with palpable tumors and 80% for those without, respectively. The survival rate of patients who did not have palpable masses and were treated with brachytherapy alone was not improved by combination with external irradiation. The time interval from the primary hysterectomy to the recurrence did not influence survival. These results suggest that the only significant prognostic factor for recurrent cervical cancer after hysterectomy is tumor size. The relationship between recurrent cervical cancer of the vaginal stump and second primary vaginal cancer is also discussed.

Original languageEnglish
Pages (from-to)927-932
Number of pages6
JournalInternational Journal of Radiation Oncology, Biology, Physics
Volume20
Issue number5
DOIs
Publication statusPublished - 1991 May 1

Keywords

  • High dose rate brachytherapy
  • Intracavitary brachytherapy
  • Recurrence at the vaginal stump
  • Recurrent cervical cancer
  • Vaginal cancer
  • Vaginal stump cancer

ASJC Scopus subject areas

  • Radiation
  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Cancer Research

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