(Chemical Equation Presented) Going green: The synthetically very important aldol reaction can proceed in water without a metal catalyst with excellent enantioselectivity. The key to the reaction is a small, synthetic organic catalyst based on trans-hydroxyproline with a siloxy group. Thus, this method is an environmentally friendly process for the synthesis of chiral molecules.
|Number of pages||4|
|Journal||Angewandte Chemie - International Edition|
|Publication status||Published - 2006 Jan 30|
- Aldol reaction
- Asymmetric synthesis
- Solvent effects
ASJC Scopus subject areas