Highly enantioselective borohydride reductions of 2-phenacylpyridine catalyzed by optically active β-ketoiminato cobalt(II) complexes

Yuhki Ohtsuka, Taketo Ikeno, Tohru Yamada

Research output: Contribution to journalArticlepeer-review

16 Citations (Scopus)

Abstract

The highly enantioselective reduction of 2-phenacylpyridine catalyzed by optically active β-ketoiminato cobalt(II) complexes with pre-modified sodium borohydride was achieved affording in high enantiomeric excess 1-phenyl-2-(2-pyridyl)ethanol, a precursor of sedamine derivatives. The enantioselective sense in the present reduction is discussed and compared to the asymmetric reduction catalyzed by other complex catalysts. Copyright (C) 2000 Elsevier Science Ltd.

Original languageEnglish
Pages (from-to)3671-3674
Number of pages4
JournalTetrahedron Asymmetry
Volume11
Issue number18
DOIs
Publication statusPublished - 2000 Sep 22

ASJC Scopus subject areas

  • Catalysis
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

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