Abstract
The highly enantioselective cyclopropanation of styrenes and diazoacetates proceeded in alcohol or aqueous alcohol in the presence of the β-ketoiminato cobalt(II) complex. Water and alcohols accelerated the reaction and improved the diastereo- and enantioselectivities. In these media, the α,α-disubstituted styrenes were smoothly cyclopropanated with high enantiomeric excess.
Original language | English |
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Pages (from-to) | 406-408 |
Number of pages | 3 |
Journal | Synlett |
Issue number | 3 |
DOIs | |
Publication status | Published - 2001 |
Keywords
- Alcohols
- Asymmetric synthesis
- Cobalt
- Cyclopropanation
- Water
ASJC Scopus subject areas
- Organic Chemistry