Abstract
The highly enantioselective cyclopropanation of styrenes and diazoacetates proceeded in alcohol or aqueous alcohol in the presence of the β-ketoiminato cobalt(II) complex. Water and alcohols accelerated the reaction and improved the diastereo- and enantioselectivities. In these media, the α,α-disubstituted styrenes were smoothly cyclopropanated with high enantiomeric excess.
| Original language | English |
|---|---|
| Pages (from-to) | 406-408 |
| Number of pages | 3 |
| Journal | Synlett |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 2001 |
Keywords
- Alcohols
- Asymmetric synthesis
- Cobalt
- Cyclopropanation
- Water
ASJC Scopus subject areas
- Organic Chemistry
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Cite this
Ikeno, T., Nishizuka, A., Sato, M., & Yamada, T. (2001). Highly enantioselective cyclopropanation in alcoholic and aqueous solvents catalyzed by optically active β-ketoiminato cobalt(II) complex. Synlett, (3), 406-408. https://doi.org/10.1055/s-2001-11416