Highly enantioselective cyclopropanation in alcoholic and aqueous solvents catalyzed by optically active β-ketoiminato cobalt(II) complex

T. Ikeno, A. Nishizuka, M. Sato, Tohru Yamada

Research output: Contribution to journal › Article

28 Citations (Scopus)

Abstract

The highly enantioselective cyclopropanation of styrenes and diazoacetates proceeded in alcohol or aqueous alcohol in the presence of the β-ketoiminato cobalt(II) complex. Water and alcohols accelerated the reaction and improved the diastereo- and enantioselectivities. In these media, the α,α-disubstituted styrenes were smoothly cyclopropanated with high enantiomeric excess.

Original languageEnglish
Pages (from-to)406-408
Number of pages3
JournalSynlett
Issue number3
Publication statusPublished - 2001

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Styrenes
Cobalt
Alcohols
Enantioselectivity
Water

Keywords

  • Alcohols
  • Asymmetric synthesis
  • Cobalt
  • Cyclopropanation
  • Water

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Highly enantioselective cyclopropanation in alcoholic and aqueous solvents catalyzed by optically active β-ketoiminato cobalt(II) complex. / Ikeno, T.; Nishizuka, A.; Sato, M.; Yamada, Tohru.

In: Synlett, No. 3, 2001, p. 406-408.

Research output: Contribution to journal › Article

Ikeno, T, Nishizuka, A, Sato, M & Yamada, T 2001, 'Highly enantioselective cyclopropanation in alcoholic and aqueous solvents catalyzed by optically active β-ketoiminato cobalt(II) complex', Synlett, no. 3, pp. 406-408.
Ikeno T, Nishizuka A, Sato M, Yamada T. Highly enantioselective cyclopropanation in alcoholic and aqueous solvents catalyzed by optically active β-ketoiminato cobalt(II) complex. Synlett. 2001;(3):406-408.
Ikeno, T. ; Nishizuka, A. ; Sato, M. ; Yamada, Tohru. / Highly enantioselective cyclopropanation in alcoholic and aqueous solvents catalyzed by optically active β-ketoiminato cobalt(II) complex. In: Synlett. 2001 ; No. 3. pp. 406-408.
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