TY - JOUR
T1 - Hippocampal and amygdalar volumes in breast cancer survivors with posttraumatic stress disorder
AU - Hara, Eriko
AU - Matsuoka, Yutaka
AU - Hakamata, Yuko
AU - Nagamine, Mitsue
AU - Inagaki, Masatoshi
AU - Imoto, Shigeru
AU - Murakami, Koji
AU - Kim, Yoshiharu
AU - Uchitomi, Yosuke
PY - 2008/1/1
Y1 - 2008/1/1
N2 - Although smaller hippocampi and amygdalae were found in cancer survivors with intrusions, associations between cancer-related posttraumatic stress disorder (PTSD) and these volumes are unknown. The authors performed MRI volumetric analyses of these regions in 15 cancer survivors with PTSD, 15 cancer survivors without PTSD, and 15 healthy comparison subjects. The authors also examined the correlation between PTSD symptom scores of the Impact of Event Scale and these volumes in the PTSD group. These volumes were not significantly different among the groups, but the intrusion score was inversely associated with the hippocampal volume. Results suggest intrusions, not PTSD diagnosis, might be associated with hippocampal volume.
AB - Although smaller hippocampi and amygdalae were found in cancer survivors with intrusions, associations between cancer-related posttraumatic stress disorder (PTSD) and these volumes are unknown. The authors performed MRI volumetric analyses of these regions in 15 cancer survivors with PTSD, 15 cancer survivors without PTSD, and 15 healthy comparison subjects. The authors also examined the correlation between PTSD symptom scores of the Impact of Event Scale and these volumes in the PTSD group. These volumes were not significantly different among the groups, but the intrusion score was inversely associated with the hippocampal volume. Results suggest intrusions, not PTSD diagnosis, might be associated with hippocampal volume.
UR - http://www.scopus.com/inward/record.url?scp=52649093910&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=52649093910&partnerID=8YFLogxK
U2 - 10.1176/jnp.2008.20.3.302
DO - 10.1176/jnp.2008.20.3.302
M3 - Article
C2 - 18806233
AN - SCOPUS:52649093910
SN - 0895-0172
VL - 20
SP - 302
EP - 308
JO - Journal of Neuropsychiatry and Clinical Neurosciences
JF - Journal of Neuropsychiatry and Clinical Neurosciences
IS - 3
ER -