Hypergonadotropic hypogonadism in a 3-year-old girl with blepharophimosis, ptosis, and epicanthus inversus syndrome

Tsutomu Ogata, Tomonobu Hasegawa, Shinya Tamai, Seiji Sato, Yukihiro Hasegawa, Nobutake Matsuo

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

We report on ovarian dysfunction in a 3-year-old girl with blepharophimosis, ptosis, and epicanthus inversus syndrome (BPES). A gonadotropin releasing hormone test showed hyperresponses of luteinizing hormone (< 0.2→7.2 mIU/ml) and follicle-stimulating hormone (7.1→44.8 mIU/ml), and a human menopause gonadotropin test yielded no estradiol response (13→11 pg/ml). The results suggest that primary ovarian failure in type I BPES can take place in early childhood.

Original languageEnglish
Pages (from-to)190-192
Number of pages3
JournalHormone Research
Volume50
Issue number3
DOIs
Publication statusPublished - 1998 Sep

Fingerprint

Hypogonadism
Follicle Stimulating Hormone
Menopause
Luteinizing Hormone
Gonadotropins
Gonadotropin-Releasing Hormone
Estradiol
Blepharophimosis, Ptosis, and Epicanthus Inversus

Keywords

  • Blepharophimosis
  • Childhood
  • Hypergonadotropic hypogonadism
  • Ovarian failure

ASJC Scopus subject areas

  • Endocrinology

Cite this

Hypergonadotropic hypogonadism in a 3-year-old girl with blepharophimosis, ptosis, and epicanthus inversus syndrome. / Ogata, Tsutomu; Hasegawa, Tomonobu; Tamai, Shinya; Sato, Seiji; Hasegawa, Yukihiro; Matsuo, Nobutake.

In: Hormone Research, Vol. 50, No. 3, 09.1998, p. 190-192.

Research output: Contribution to journalArticle

Ogata, Tsutomu ; Hasegawa, Tomonobu ; Tamai, Shinya ; Sato, Seiji ; Hasegawa, Yukihiro ; Matsuo, Nobutake. / Hypergonadotropic hypogonadism in a 3-year-old girl with blepharophimosis, ptosis, and epicanthus inversus syndrome. In: Hormone Research. 1998 ; Vol. 50, No. 3. pp. 190-192.
@article{9f6f3926a3e54abeb0a1667b39cba08e,
title = "Hypergonadotropic hypogonadism in a 3-year-old girl with blepharophimosis, ptosis, and epicanthus inversus syndrome",
abstract = "We report on ovarian dysfunction in a 3-year-old girl with blepharophimosis, ptosis, and epicanthus inversus syndrome (BPES). A gonadotropin releasing hormone test showed hyperresponses of luteinizing hormone (< 0.2→7.2 mIU/ml) and follicle-stimulating hormone (7.1→44.8 mIU/ml), and a human menopause gonadotropin test yielded no estradiol response (13→11 pg/ml). The results suggest that primary ovarian failure in type I BPES can take place in early childhood.",
keywords = "Blepharophimosis, Childhood, Hypergonadotropic hypogonadism, Ovarian failure",
author = "Tsutomu Ogata and Tomonobu Hasegawa and Shinya Tamai and Seiji Sato and Yukihiro Hasegawa and Nobutake Matsuo",
year = "1998",
month = "9",
doi = "10.1159/000023272",
language = "English",
volume = "50",
pages = "190--192",
journal = "Hormone Research in Paediatrics",
issn = "1663-2818",
publisher = "S. Karger AG",
number = "3",

}

TY - JOUR

T1 - Hypergonadotropic hypogonadism in a 3-year-old girl with blepharophimosis, ptosis, and epicanthus inversus syndrome

AU - Ogata, Tsutomu

AU - Hasegawa, Tomonobu

AU - Tamai, Shinya

AU - Sato, Seiji

AU - Hasegawa, Yukihiro

AU - Matsuo, Nobutake

PY - 1998/9

Y1 - 1998/9

N2 - We report on ovarian dysfunction in a 3-year-old girl with blepharophimosis, ptosis, and epicanthus inversus syndrome (BPES). A gonadotropin releasing hormone test showed hyperresponses of luteinizing hormone (< 0.2→7.2 mIU/ml) and follicle-stimulating hormone (7.1→44.8 mIU/ml), and a human menopause gonadotropin test yielded no estradiol response (13→11 pg/ml). The results suggest that primary ovarian failure in type I BPES can take place in early childhood.

AB - We report on ovarian dysfunction in a 3-year-old girl with blepharophimosis, ptosis, and epicanthus inversus syndrome (BPES). A gonadotropin releasing hormone test showed hyperresponses of luteinizing hormone (< 0.2→7.2 mIU/ml) and follicle-stimulating hormone (7.1→44.8 mIU/ml), and a human menopause gonadotropin test yielded no estradiol response (13→11 pg/ml). The results suggest that primary ovarian failure in type I BPES can take place in early childhood.

KW - Blepharophimosis

KW - Childhood

KW - Hypergonadotropic hypogonadism

KW - Ovarian failure

UR - http://www.scopus.com/inward/record.url?scp=0031686450&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031686450&partnerID=8YFLogxK

U2 - 10.1159/000023272

DO - 10.1159/000023272

M3 - Article

C2 - 9762009

AN - SCOPUS:0031686450

VL - 50

SP - 190

EP - 192

JO - Hormone Research in Paediatrics

JF - Hormone Research in Paediatrics

SN - 1663-2818

IS - 3

ER -