Identifying improvable employment-related factors in schizophrenia patients

Tadashi Hasegawa, Tasuku Hashimoto, Nobuhisa Kanahara, Hiroshi Yamanaka, Minoru Ishige, Yasunori Sato, Masaomi Iyo

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Although many studies report various factors related to future employment of schizophrenia patients, few identify the treatable or improvable ones. The responses to the first year of treatment and daily antipsychotic drug doses may be the treatable and improvable factors. We surveyed 235 schizophrenia outpatients in three facilities, of whom 129 and 106 were employed and unemployed, respectively. Through face-to-face interviews and medical record reviews, we investigated symptomatic and social functioning responses to the first year of treatment using the Global Assessment of Psychopathology Scale (GAPS) and the Social and Occupational Functioning Assessment Scale (SOFAS). We investigated daily antipsychotic drug doses and other clinical assessments at the interview time. Finally, we used multivariable logistic regression analysis. SOFAS-measured improvements in the period 6 to 12 months after beginning treatment and daily antipsychotic drug doses equivalent to less than 600 mg of chlorpromazine were identified as an employment-related factor, but GAPS-measure improvements were not. Social functioning improvements in the period 6 to 12 months after beginning treatment and low-to-moderate daily antipsychotic drug doses were detected as employment-related factors, suggesting that early efforts to improve social functioning and optimize antipsychotic drug doses could lead to future employment for schizophrenia patients.

Original languageEnglish
Pages (from-to)199-205
Number of pages7
JournalPsychiatry Research
Volume266
DOIs
Publication statusPublished - 2018 Aug 1
Externally publishedYes

Fingerprint

Antipsychotic Agents
Schizophrenia
Psychopathology
Interviews
Chlorpromazine
Therapeutics
Medical Records
Outpatients
Logistic Models
Regression Analysis

Keywords

  • Antipsychotics
  • Early improvement
  • Social functioning

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

Cite this

Hasegawa, T., Hashimoto, T., Kanahara, N., Yamanaka, H., Ishige, M., Sato, Y., & Iyo, M. (2018). Identifying improvable employment-related factors in schizophrenia patients. Psychiatry Research, 266, 199-205. https://doi.org/10.1016/j.psychres.2018.05.064

Identifying improvable employment-related factors in schizophrenia patients. / Hasegawa, Tadashi; Hashimoto, Tasuku; Kanahara, Nobuhisa; Yamanaka, Hiroshi; Ishige, Minoru; Sato, Yasunori; Iyo, Masaomi.

In: Psychiatry Research, Vol. 266, 01.08.2018, p. 199-205.

Research output: Contribution to journalArticle

Hasegawa, T, Hashimoto, T, Kanahara, N, Yamanaka, H, Ishige, M, Sato, Y & Iyo, M 2018, 'Identifying improvable employment-related factors in schizophrenia patients', Psychiatry Research, vol. 266, pp. 199-205. https://doi.org/10.1016/j.psychres.2018.05.064
Hasegawa, Tadashi ; Hashimoto, Tasuku ; Kanahara, Nobuhisa ; Yamanaka, Hiroshi ; Ishige, Minoru ; Sato, Yasunori ; Iyo, Masaomi. / Identifying improvable employment-related factors in schizophrenia patients. In: Psychiatry Research. 2018 ; Vol. 266. pp. 199-205.
@article{cd2ff2db4c004141ae7087e35dd71ea0,
title = "Identifying improvable employment-related factors in schizophrenia patients",
abstract = "Although many studies report various factors related to future employment of schizophrenia patients, few identify the treatable or improvable ones. The responses to the first year of treatment and daily antipsychotic drug doses may be the treatable and improvable factors. We surveyed 235 schizophrenia outpatients in three facilities, of whom 129 and 106 were employed and unemployed, respectively. Through face-to-face interviews and medical record reviews, we investigated symptomatic and social functioning responses to the first year of treatment using the Global Assessment of Psychopathology Scale (GAPS) and the Social and Occupational Functioning Assessment Scale (SOFAS). We investigated daily antipsychotic drug doses and other clinical assessments at the interview time. Finally, we used multivariable logistic regression analysis. SOFAS-measured improvements in the period 6 to 12 months after beginning treatment and daily antipsychotic drug doses equivalent to less than 600 mg of chlorpromazine were identified as an employment-related factor, but GAPS-measure improvements were not. Social functioning improvements in the period 6 to 12 months after beginning treatment and low-to-moderate daily antipsychotic drug doses were detected as employment-related factors, suggesting that early efforts to improve social functioning and optimize antipsychotic drug doses could lead to future employment for schizophrenia patients.",
keywords = "Antipsychotics, Early improvement, Social functioning",
author = "Tadashi Hasegawa and Tasuku Hashimoto and Nobuhisa Kanahara and Hiroshi Yamanaka and Minoru Ishige and Yasunori Sato and Masaomi Iyo",
year = "2018",
month = "8",
day = "1",
doi = "10.1016/j.psychres.2018.05.064",
language = "English",
volume = "266",
pages = "199--205",
journal = "Psychiatry Research",
issn = "0165-1781",
publisher = "Elsevier Ireland Ltd",

}

TY - JOUR

T1 - Identifying improvable employment-related factors in schizophrenia patients

AU - Hasegawa, Tadashi

AU - Hashimoto, Tasuku

AU - Kanahara, Nobuhisa

AU - Yamanaka, Hiroshi

AU - Ishige, Minoru

AU - Sato, Yasunori

AU - Iyo, Masaomi

PY - 2018/8/1

Y1 - 2018/8/1

N2 - Although many studies report various factors related to future employment of schizophrenia patients, few identify the treatable or improvable ones. The responses to the first year of treatment and daily antipsychotic drug doses may be the treatable and improvable factors. We surveyed 235 schizophrenia outpatients in three facilities, of whom 129 and 106 were employed and unemployed, respectively. Through face-to-face interviews and medical record reviews, we investigated symptomatic and social functioning responses to the first year of treatment using the Global Assessment of Psychopathology Scale (GAPS) and the Social and Occupational Functioning Assessment Scale (SOFAS). We investigated daily antipsychotic drug doses and other clinical assessments at the interview time. Finally, we used multivariable logistic regression analysis. SOFAS-measured improvements in the period 6 to 12 months after beginning treatment and daily antipsychotic drug doses equivalent to less than 600 mg of chlorpromazine were identified as an employment-related factor, but GAPS-measure improvements were not. Social functioning improvements in the period 6 to 12 months after beginning treatment and low-to-moderate daily antipsychotic drug doses were detected as employment-related factors, suggesting that early efforts to improve social functioning and optimize antipsychotic drug doses could lead to future employment for schizophrenia patients.

AB - Although many studies report various factors related to future employment of schizophrenia patients, few identify the treatable or improvable ones. The responses to the first year of treatment and daily antipsychotic drug doses may be the treatable and improvable factors. We surveyed 235 schizophrenia outpatients in three facilities, of whom 129 and 106 were employed and unemployed, respectively. Through face-to-face interviews and medical record reviews, we investigated symptomatic and social functioning responses to the first year of treatment using the Global Assessment of Psychopathology Scale (GAPS) and the Social and Occupational Functioning Assessment Scale (SOFAS). We investigated daily antipsychotic drug doses and other clinical assessments at the interview time. Finally, we used multivariable logistic regression analysis. SOFAS-measured improvements in the period 6 to 12 months after beginning treatment and daily antipsychotic drug doses equivalent to less than 600 mg of chlorpromazine were identified as an employment-related factor, but GAPS-measure improvements were not. Social functioning improvements in the period 6 to 12 months after beginning treatment and low-to-moderate daily antipsychotic drug doses were detected as employment-related factors, suggesting that early efforts to improve social functioning and optimize antipsychotic drug doses could lead to future employment for schizophrenia patients.

KW - Antipsychotics

KW - Early improvement

KW - Social functioning

UR - http://www.scopus.com/inward/record.url?scp=85047818216&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85047818216&partnerID=8YFLogxK

U2 - 10.1016/j.psychres.2018.05.064

DO - 10.1016/j.psychres.2018.05.064

M3 - Article

C2 - 29870957

AN - SCOPUS:85047818216

VL - 266

SP - 199

EP - 205

JO - Psychiatry Research

JF - Psychiatry Research

SN - 0165-1781

ER -