Idiopathic hyperammonemia following allogeneic bone marrow transplantation for refractory lymphoma

R. Watanabe, Shinichiro Okamoto, A. Asahi, Takehiko Mori, N. Takayama, Y. Ikeda

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Idiopathic hyperammonemia (IHA) is a rare but serious complication of stem cell transplantation. We report a patient with immunoblastic lymphoadenopathy-like T-cell lymphoma who developed IHA 10 days after allogeneic bone marrow transplantation from an HLA-matched unrelated donor. Despite intensive supportive care, the patient died due to this metabolic disorder two days later. Being mindful of the possibility of IHA in patients who develop confusion and respiratory alkalosis soon after stem cell transplantation would allow earlier treatment and might improve the chance of survival.

Original languageEnglish
Pages (from-to)1285-1288
Number of pages4
Journal[Rinshō ketsueki] The Japanese journal of clinical hematology
Volume41
Issue number12
Publication statusPublished - 2000

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Hyperammonemia
Homologous Transplantation
Bone Marrow Transplantation
Lymphoma
Stem Cell Transplantation
Respiratory Alkalosis
Unrelated Donors
T-Cell Lymphoma
Critical Care
Survival
Therapeutics

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Idiopathic hyperammonemia following allogeneic bone marrow transplantation for refractory lymphoma. / Watanabe, R.; Okamoto, Shinichiro; Asahi, A.; Mori, Takehiko; Takayama, N.; Ikeda, Y.

In: [Rinshō ketsueki] The Japanese journal of clinical hematology, Vol. 41, No. 12, 2000, p. 1285-1288.

Research output: Contribution to journalArticle

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