Ileal duodenal fistula with malnutrition caused by crohn disease, improved by operation

Shimpei Matsui, Koji Okabayashi, Hirotoshi Hasegawa, Masashi Tsuruta, Ryo Seishima, Hidena Takahashi, Toru Yamada, Mutsuhito Matsuda, Masayuki Shimoda, Yuko Kitagawa

Research output: Contribution to journalArticlepeer-review


Crohn disease can develop stricture and perforation in any part of the alimentary tract. However, duodenal Crohn disease is rarely observed and often difficult to treat. A 52-year-old man with Crohn disease presented with general fatigue, appetite loss, abdominal pain and diarrhea. Although several drugs (steroids, 5-ASA, immuno-modulator, anti-TNF-a antibody) were administrated considering recurrence of Crohn disease, his manifestations did not disappear and his nutritional condition was also worsened. Several examinations revealed his malnutrition due to bowel short-circuiting by duodenal fistula to terminal ileum adding to refractory Crohn disease. To remove the shortcircuiting, operation was performed. After removing the short-circuiting and closing the fistula, ileal partial resection was performed. Duodenum was diverted, then Billroth-II gastrojejunostomy and jejunostomy was carried out. After the operation, he achieved maintenance therapy using anti-TNF-a antibody. Consequently, we have succeeded in improvement of nutritional status and have not identified any recurrence of Crohn disease for postoperative eight months.

Original languageEnglish
Pages (from-to)1157-1163
Number of pages7
JournalJapanese Journal of Gastroenterological Surgery
Issue number11
Publication statusPublished - 2016


  • Crohn disease
  • Ileal-duodenal fistula
  • Malnutrition

ASJC Scopus subject areas

  • Surgery
  • Gastroenterology


Dive into the research topics of 'Ileal duodenal fistula with malnutrition caused by crohn disease, improved by operation'. Together they form a unique fingerprint.

Cite this