Imaging of large early and early advanced hepatocellular carcinomas of more than 5 cm in diameter: Report of two cases

Kimihito Fujii, Kenichi Takayasu, Takao Ohkubo, Yukio Muramatsu, Yasunori Mizuguchi, Susumu Yamasaki, Michiie Sakamoto, Takehiko Abe

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

In an attempt to clarify the imaging characteristics of large early and early advanced hepatocellular carcinoma (HCC), we present two such cases which were greater than 5 cm in diameter. One case had four early HCCs and the other had early advanced HCC which was followed for five years and nine months. Multiphasic CT, CT arteriography (CTA), CT arterial portography (CTAP), and MR imaging were performed. Early HCC was shown as a low density mass by multiphasic contrast CT, CTAP and as a hyperintense mass on a T1-weighted image (WI) and isointense on T2WI. Early advanced HCC was demonstrated as a hypodense mass with hyperenhancing interior nodules on CTA, and isodense with hypodense internal foci on CTAP. One follow-up case showed a multi-step progression from early to early advanced HCC, and finally to overtly advanced HCC. Despite the unusually large size of these two tumors, the findings of multiphasic CT, CTA, CTAP, and MR imaging were consistent with those seen in common-sized (less than 2 cm) early and early advanced HCCs. Multi-step progression of hepatocarcinogenesis was observed in one case.

Original languageEnglish
Pages (from-to)1085-1092
Number of pages8
JournalHepato-gastroenterology
Volume45
Issue number22
Publication statusPublished - 1998 Sep 10
Externally publishedYes

Keywords

  • CT arterial portography
  • CT arteriography
  • Early hepatocellular carcinoma

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

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