Imbibed immiscible solvent splits aqueous solution into a two-dimensional droplet array without precise pipetting or pumping

H. Yasuga; Norihisa Miki

Imbibed immiscible solvent splits aqueous solution into a two-dimensional droplet array without precise pipetting or pumping

H. Yasuga, Norihisa Miki

Department of Mechanical Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

3 Citations (Scopus)

Abstract

This paper proposes a method to generate two-dimensional (2D) arrays of droplets without precise pipetting or pumping. The 2D arrays of droplets are powerful tools for high throughput and low-cost biological assays or medical diagnosis. Here, such arrays are generated by simply introducing aqueous solution and immiscible solvent into an array of connected circular wells; the aqueous solution impregnated in the array are split into droplets in every single well by injecting the immiscible solvent. Droplet generation was investigated according to well geometry. Droplet array including 2D concentration gradient of two inks are demonstrated to show applicability to biological assays.

Original language	English
Title of host publication	20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
Publisher	Chemical and Biological Microsystems Society
Pages	83-84
Number of pages	2
ISBN (Electronic)	9780979806490
Publication status	Published - 2016
Event	20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 - Dublin, Ireland Duration: 2016 Oct 9 → 2016 Oct 13

Other

Other	20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
Country	Ireland
City	Dublin
Period	16/10/9 → 16/10/13

Keywords

Concentration gradient
Droplet array

ASJC Scopus subject areas

Control and Systems Engineering

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Cite this

Imbibed immiscible solvent splits aqueous solution into a two-dimensional droplet array without precise pipetting or pumping. / Yasuga, H.; Miki, Norihisa.

20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016. Chemical and Biological Microsystems Society, 2016. p. 83-84.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Yasuga, H & Miki, N 2016, Imbibed immiscible solvent splits aqueous solution into a two-dimensional droplet array without precise pipetting or pumping. in 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016. Chemical and Biological Microsystems Society, pp. 83-84, 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016, Dublin, Ireland, 16/10/9.

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