Abstract
This paper proposes a method to generate two-dimensional (2D) arrays of droplets without precise pipetting or pumping. The 2D arrays of droplets are powerful tools for high throughput and low-cost biological assays or medical diagnosis. Here, such arrays are generated by simply introducing aqueous solution and immiscible solvent into an array of connected circular wells; the aqueous solution impregnated in the array are split into droplets in every single well by injecting the immiscible solvent. Droplet generation was investigated according to well geometry. Droplet array including 2D concentration gradient of two inks are demonstrated to show applicability to biological assays.
| Original language | English |
|---|---|
| Title of host publication | 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 |
| Publisher | Chemical and Biological Microsystems Society |
| Pages | 83-84 |
| Number of pages | 2 |
| ISBN (Electronic) | 9780979806490 |
| Publication status | Published - 2016 |
| Event | 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 - Dublin, Ireland Duration: 2016 Oct 9 → 2016 Oct 13 |
Other
| Other | 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 |
|---|---|
| Country | Ireland |
| City | Dublin |
| Period | 16/10/9 → 16/10/13 |
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Keywords
- Concentration gradient
- Droplet array
ASJC Scopus subject areas
- Control and Systems Engineering
Cite this
Imbibed immiscible solvent splits aqueous solution into a two-dimensional droplet array without precise pipetting or pumping. / Yasuga, H.; Miki, Norihisa.
20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016. Chemical and Biological Microsystems Society, 2016. p. 83-84.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Imbibed immiscible solvent splits aqueous solution into a two-dimensional droplet array without precise pipetting or pumping
AU - Yasuga, H.
AU - Miki, Norihisa
PY - 2016
Y1 - 2016
N2 - This paper proposes a method to generate two-dimensional (2D) arrays of droplets without precise pipetting or pumping. The 2D arrays of droplets are powerful tools for high throughput and low-cost biological assays or medical diagnosis. Here, such arrays are generated by simply introducing aqueous solution and immiscible solvent into an array of connected circular wells; the aqueous solution impregnated in the array are split into droplets in every single well by injecting the immiscible solvent. Droplet generation was investigated according to well geometry. Droplet array including 2D concentration gradient of two inks are demonstrated to show applicability to biological assays.
AB - This paper proposes a method to generate two-dimensional (2D) arrays of droplets without precise pipetting or pumping. The 2D arrays of droplets are powerful tools for high throughput and low-cost biological assays or medical diagnosis. Here, such arrays are generated by simply introducing aqueous solution and immiscible solvent into an array of connected circular wells; the aqueous solution impregnated in the array are split into droplets in every single well by injecting the immiscible solvent. Droplet generation was investigated according to well geometry. Droplet array including 2D concentration gradient of two inks are demonstrated to show applicability to biological assays.
KW - Concentration gradient
KW - Droplet array
UR - http://www.scopus.com/inward/record.url?scp=85014205914&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85014205914&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:85014205914
SP - 83
EP - 84
BT - 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
PB - Chemical and Biological Microsystems Society
ER -