Imbibed immiscible solvent splits aqueous solution into a two-dimensional droplet array without precise pipetting or pumping

H. Yasuga, Norihisa Miki

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

3 Citations (Scopus)

Abstract

This paper proposes a method to generate two-dimensional (2D) arrays of droplets without precise pipetting or pumping. The 2D arrays of droplets are powerful tools for high throughput and low-cost biological assays or medical diagnosis. Here, such arrays are generated by simply introducing aqueous solution and immiscible solvent into an array of connected circular wells; the aqueous solution impregnated in the array are split into droplets in every single well by injecting the immiscible solvent. Droplet generation was investigated according to well geometry. Droplet array including 2D concentration gradient of two inks are demonstrated to show applicability to biological assays.

Original languageEnglish
Title of host publication20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
PublisherChemical and Biological Microsystems Society
Pages83-84
Number of pages2
ISBN (Electronic)9780979806490
Publication statusPublished - 2016
Event20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 - Dublin, Ireland
Duration: 2016 Oct 9 → 2016 Oct 13

Other

Other20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
CountryIreland
CityDublin
Period16/10/9 → 16/10/13

Keywords

  • Concentration gradient
  • Droplet array

ASJC Scopus subject areas

  • Control and Systems Engineering

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    • Cite this

    Yasuga, H., & Miki, N. (2016). Imbibed immiscible solvent splits aqueous solution into a two-dimensional droplet array without precise pipetting or pumping. In 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 (pp. 83-84). Chemical and Biological Microsystems Society.