Immunological adjuvant activity of pectinioside a, the steroidal saponin from the starfish Patiria pectinifera

Osamu Kawase, Osamu Ohno, Kiyotake Suenaga, Xuenan Xuan

Research output: Contribution to journalArticlepeer-review

Abstract

The steroidal saponin, pectinioside A, was isolated from the starfish, Patiria pectinifera. When it was subcutaneously injected into mice with ovalbumin (OVA), it facilitated the production of OVA-specific total IgG and IgG1 but not IgG2a. To our knowledge, this is the first report suggesting that starfish saponin has the potential to be an immunological adjuvant, stimulating Th2 type immune response.

Original languageEnglish
Pages (from-to)605-606
Number of pages2
JournalNatural product communications
Volume11
Issue number5
DOIs
Publication statusPublished - 2016 May

Keywords

  • Immunologcal adjuvant
  • Patiria pectinifera
  • Pectinioside
  • Starfish
  • Steroidal saponin

ASJC Scopus subject areas

  • Pharmacology
  • Plant Science
  • Drug Discovery
  • Complementary and alternative medicine

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