Impact of comorbidity index on morbidity and survival in non-small cell lung cancer

Sotaro Otake, Takashi Ohtsuka, Keisuke Asakura, Ikuo Kamiyama, Mitsutomo Kohno

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)

Abstract

Background The number of surgeries in older patients with comorbidities is constantly growing. The present study examined the impact of comorbidity on postoperative complications and long-term survival in patients with completely resected non-small cell cancer. Methods Between 2004 and 2008, 423 patients with non-small cell lung cancer underwent complete resection. A retrospective comparison of perioperative mortality, morbidity, Charlson comorbidity index (CCI), and postoperative length of hospital stay was performed. Results The number of patients with CCI 0, 1-2, and ≥3 was 226, 170 and 27, respectively. The 5-year overall survival was 88% among patients with CCI 0, and 84% in those with CCI ≥1 (p = 0.05) in all pathological stages. The CCI 0 group had significantly better overall survival than CCI 0 group and 30 (15%) in the CCI ≥1 group (p = 0.024). Length of stay was shorter in the CCI 0 group (11 ± 5 days) than in the CCI ≥1 group (15 ± 19 days, p = 0.015). Conclusions A high CCI correlated with higher postoperative morbidity and longer length of stay. We identified better a prognosis in patients with CCI 0 compared to those with CCI 1-2.

Original languageEnglish
Pages (from-to)30-33
Number of pages4
JournalAsian Cardiovascular and Thoracic Annals
Volume24
Issue number1
DOIs
Publication statusPublished - 2016 Jan 1

Keywords

  • Carcinoma
  • Comorbidity
  • Health status indicators
  • Lung neoplasms
  • Survival analysis
  • non-small cell lung cancer

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

Fingerprint

Dive into the research topics of 'Impact of comorbidity index on morbidity and survival in non-small cell lung cancer'. Together they form a unique fingerprint.

Cite this