Impact of comorbidity index on morbidity and survival in non-small cell lung cancer

Sotaro Otake, Takashi Ohtsuka, Keisuke Asakura, Ikuo Kamiyama, Mitsutomo Kohno

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Background The number of surgeries in older patients with comorbidities is constantly growing. The present study examined the impact of comorbidity on postoperative complications and long-term survival in patients with completely resected non-small cell cancer. Methods Between 2004 and 2008, 423 patients with non-small cell lung cancer underwent complete resection. A retrospective comparison of perioperative mortality, morbidity, Charlson comorbidity index (CCI), and postoperative length of hospital stay was performed. Results The number of patients with CCI 0, 1-2, and ≥3 was 226, 170 and 27, respectively. The 5-year overall survival was 88% among patients with CCI 0, and 84% in those with CCI ≥1 (p = 0.05) in all pathological stages. The CCI 0 group had significantly better overall survival than CCI 0 group and 30 (15%) in the CCI ≥1 group (p = 0.024). Length of stay was shorter in the CCI 0 group (11 ± 5 days) than in the CCI ≥1 group (15 ± 19 days, p = 0.015). Conclusions A high CCI correlated with higher postoperative morbidity and longer length of stay. We identified better a prognosis in patients with CCI 0 compared to those with CCI 1-2.

Original languageEnglish
Pages (from-to)30-33
Number of pages4
JournalAsian Cardiovascular and Thoracic Annals
Volume24
Issue number1
DOIs
Publication statusPublished - 2016 Jan 1

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Non-Small Cell Lung Carcinoma
Comorbidity
Morbidity
Survival
Length of Stay

Keywords

  • Carcinoma
  • Comorbidity
  • Health status indicators
  • Lung neoplasms
  • non-small cell lung cancer
  • Survival analysis

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery
  • Pulmonary and Respiratory Medicine

Cite this

Impact of comorbidity index on morbidity and survival in non-small cell lung cancer. / Otake, Sotaro; Ohtsuka, Takashi; Asakura, Keisuke; Kamiyama, Ikuo; Kohno, Mitsutomo.

In: Asian Cardiovascular and Thoracic Annals, Vol. 24, No. 1, 01.01.2016, p. 30-33.

Research output: Contribution to journalArticle

Otake, Sotaro ; Ohtsuka, Takashi ; Asakura, Keisuke ; Kamiyama, Ikuo ; Kohno, Mitsutomo. / Impact of comorbidity index on morbidity and survival in non-small cell lung cancer. In: Asian Cardiovascular and Thoracic Annals. 2016 ; Vol. 24, No. 1. pp. 30-33.
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