IMPACT OF OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY REVIEW STRATEGY ON DETECTION OF CHOROIDAL NEOVASCULARIZATION

Amy S. Babiuch, Atsuro Uchida, Natalia Figueiredo, Ming Hu, Mehnaz Khan, Sunil K. Srivastava, Rishi P. Singh, Aleksandra Rachitskaya, Peter K. Kaiser, Jamie L. Reese, Justis P. Ehlers

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

PURPOSE: To compare optical coherence tomography angiography (OCTA) review strategies for optimizing choroidal neovascularization (CNV) detection. METHODS: Eyes with CNV in the differential diagnosis were imaged with the Avanti RTVue XR HD (Optovue, Fremont, CA). Three modalities of review for CNV presence were used in each case: a single report generated using automated segmentation within Avanti software; a continuous slab descent video OCTA export; and a manual segmentation approach using cross-sectional OCT with decorrelation signal overlay. Scans were reviewed by two masked expert reviewers; a third reviewer was used for discrepancies. RESULTS: The study included 421 eyes, and 350 eyes had reports deemed sufficient quality for interpretation. Choroidal neovascularization was in the differential diagnosis in 107 of 350 patients. Overall CNV was identified in 55% (59/107) eyes. In those eyes with CNV, the automated segmentation identified CNV in 56% (33/59) of cases, continuous slab descent method identified CNV in 53% (31/59) of cases, and the manual segmentation group identified CNV in 92% (54/59) of cases. CONCLUSION: Review strategies for detection of CNV on OCTA were highest using the manual segmentation method as compared to both the automated report and continuous slab descent methods. Although the manual segmentation method had a higher rate of detection, the practical aspects of the time required for segmentation make this method challenging in routine clinical practice.

Original languageEnglish
Pages (from-to)672-678
Number of pages7
JournalRetina (Philadelphia, Pa.)
Volume40
Issue number4
DOIs
Publication statusPublished - 2020 Apr 1
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology

Fingerprint Dive into the research topics of 'IMPACT OF OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY REVIEW STRATEGY ON DETECTION OF CHOROIDAL NEOVASCULARIZATION'. Together they form a unique fingerprint.

  • Cite this

    Babiuch, A. S., Uchida, A., Figueiredo, N., Hu, M., Khan, M., Srivastava, S. K., Singh, R. P., Rachitskaya, A., Kaiser, P. K., Reese, J. L., & Ehlers, J. P. (2020). IMPACT OF OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY REVIEW STRATEGY ON DETECTION OF CHOROIDAL NEOVASCULARIZATION. Retina (Philadelphia, Pa.), 40(4), 672-678. https://doi.org/10.1097/IAE.0000000000002443