Impact of smoking on the age at diagnosis of upper tract urothelial carcinoma: Subanalysis of the Japanese Urological Association multi-institutional national database

Cancer Registration Committee of the Japanese Urological Association

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Objectives: To examine the influence of smoking history on the diagnosis and other tumor characteristics of upper tract urothelial carcinoma in Japan. Methods: A total of 1509 patients with upper tract urothelial carcinoma who were diagnosed in 2005 from 348 Japanese institutions were registered using the multi-institutional national database of the Japanese Urological Association and included in this analysis. Clinical data of the patients were collected in 2011. The associations between the patients' self-reported smoking history and their age at the diagnosis of upper tract urothelial carcinoma, sex, pathological T stage and tumor grade were analyzed. Results: The mean age at the diagnosis of upper tract urothelial carcinoma was approximately 5 years earlier for the 238 current smokers than for the 618 current non-smokers (P <0.0001). Similar associations between smoking and the early diagnosis of upper tract urothelial carcinoma were shown in the sex subgroups and in subgroups stratified by pathological T stages. Among the current smokers, the age at diagnosis for the smoking ≥20 cigarettes per day group was 6.5 years lower than that of the

Original languageEnglish
Pages (from-to)1023-1027
Number of pages5
JournalInternational Journal of Urology
Volume22
Issue number11
DOIs
Publication statusPublished - 2015 Nov 1

    Fingerprint

Keywords

  • Age at diagnosis
  • Japanese
  • Smoking
  • Upper tract urothelial carcinoma

ASJC Scopus subject areas

  • Urology

Cite this