Abstract
Background Underfilling or overfilling of balloon-expandable transcatheter heart valves (THVs) during transcatheter aortic valve implantation (TAVI) is commonly used to improve conformity to small or calcified annuli in order to avoid serious complications. However, little is known about this technique. This study assessed the effects of underfilling and overfilling of THVs. Methods and results Data from 213 consecutive TAVI patients treated with balloon-expandable THVs in 4 Japanese centers between October 2013 and December 2014 were prospectively analyzed; 23-mm and 26-mm THVs were implanted in 96 cases (56 underfilling, 22 nominal filling, and 18 overfilling) and 38 cases (23 underfilling and 15 nominal filling), respectively. Pre/postprocedural multidetector computed tomography (MDCT) and echocardiographic data were compared. MDCT revealed that the minimum area of the underfilled 23-mm THVs was significantly decreased compared to that of nominal filled and overfilled THVs (308.3 SD 26.1 vs. 333.9 SD 14.7 vs. 347.8 SD 21.3 mm2, respectively, p 2, respectively, p = 0.0004). The postprocedural transvalvular gradient of underfilled 23-mm THVs was significantly higher than that of nominal filled and overfilled THVs, while there were no differences for 26-mm THVs. Conclusions Underfilling or overfilling of THVs is safe and feasible, conforming to the original annulus and covering a continuous range of annular sizes with limited THV size options. However, care should be taken when underfilling 23-mm THVs due to the potential for increased transvalvular gradient.
| Original language | English |
|---|---|
| Pages (from-to) | 738-744 |
| Number of pages | 7 |
| Journal | International Journal of Cardiology |
| Volume | 222 |
| DOIs | |
| Publication status | Published - 2016 Nov 1 |
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Keywords
- Aortic stenosis
- Multidetector computed tomography
- Overfilling
- Transcatheter aortic valve implantation
- Underfilling
ASJC Scopus subject areas
- Medicine(all)
- Cardiology and Cardiovascular Medicine
Cite this
Impact of underfilling and overfilling in balloon-expandable transcatheter aortic valve implantation assessed by multidetector computed tomography : Insights from the Optimized CathEter vAlvular iNtervention (OCEAN-TAVI) registry. / Yashima, Fumiaki; Yamamoto, Masanori; Watanabe, Yusuke; Takagi, Kensuke; Yamada, Yoshitake; Inohara, Taku; Yanagisawa, Ryo; Tanaka, Makoto; Arai, Takahide; Shimizu, Hideyuki; Jinzaki, Masahiro; Kozuma, Ken; Fukuda, Keiichi; Suzuki, Takahiko; Hayashida, Kentaro.
In: International Journal of Cardiology, Vol. 222, 01.11.2016, p. 738-744.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Impact of underfilling and overfilling in balloon-expandable transcatheter aortic valve implantation assessed by multidetector computed tomography
T2 - Insights from the Optimized CathEter vAlvular iNtervention (OCEAN-TAVI) registry
AU - Yashima, Fumiaki
AU - Yamamoto, Masanori
AU - Watanabe, Yusuke
AU - Takagi, Kensuke
AU - Yamada, Yoshitake
AU - Inohara, Taku
AU - Yanagisawa, Ryo
AU - Tanaka, Makoto
AU - Arai, Takahide
AU - Shimizu, Hideyuki
AU - Jinzaki, Masahiro
AU - Kozuma, Ken
AU - Fukuda, Keiichi
AU - Suzuki, Takahiko
AU - Hayashida, Kentaro
PY - 2016/11/1
Y1 - 2016/11/1
N2 - Background Underfilling or overfilling of balloon-expandable transcatheter heart valves (THVs) during transcatheter aortic valve implantation (TAVI) is commonly used to improve conformity to small or calcified annuli in order to avoid serious complications. However, little is known about this technique. This study assessed the effects of underfilling and overfilling of THVs. Methods and results Data from 213 consecutive TAVI patients treated with balloon-expandable THVs in 4 Japanese centers between October 2013 and December 2014 were prospectively analyzed; 23-mm and 26-mm THVs were implanted in 96 cases (56 underfilling, 22 nominal filling, and 18 overfilling) and 38 cases (23 underfilling and 15 nominal filling), respectively. Pre/postprocedural multidetector computed tomography (MDCT) and echocardiographic data were compared. MDCT revealed that the minimum area of the underfilled 23-mm THVs was significantly decreased compared to that of nominal filled and overfilled THVs (308.3 SD 26.1 vs. 333.9 SD 14.7 vs. 347.8 SD 21.3 mm2, respectively, p 2, respectively, p = 0.0004). The postprocedural transvalvular gradient of underfilled 23-mm THVs was significantly higher than that of nominal filled and overfilled THVs, while there were no differences for 26-mm THVs. Conclusions Underfilling or overfilling of THVs is safe and feasible, conforming to the original annulus and covering a continuous range of annular sizes with limited THV size options. However, care should be taken when underfilling 23-mm THVs due to the potential for increased transvalvular gradient.
AB - Background Underfilling or overfilling of balloon-expandable transcatheter heart valves (THVs) during transcatheter aortic valve implantation (TAVI) is commonly used to improve conformity to small or calcified annuli in order to avoid serious complications. However, little is known about this technique. This study assessed the effects of underfilling and overfilling of THVs. Methods and results Data from 213 consecutive TAVI patients treated with balloon-expandable THVs in 4 Japanese centers between October 2013 and December 2014 were prospectively analyzed; 23-mm and 26-mm THVs were implanted in 96 cases (56 underfilling, 22 nominal filling, and 18 overfilling) and 38 cases (23 underfilling and 15 nominal filling), respectively. Pre/postprocedural multidetector computed tomography (MDCT) and echocardiographic data were compared. MDCT revealed that the minimum area of the underfilled 23-mm THVs was significantly decreased compared to that of nominal filled and overfilled THVs (308.3 SD 26.1 vs. 333.9 SD 14.7 vs. 347.8 SD 21.3 mm2, respectively, p 2, respectively, p = 0.0004). The postprocedural transvalvular gradient of underfilled 23-mm THVs was significantly higher than that of nominal filled and overfilled THVs, while there were no differences for 26-mm THVs. Conclusions Underfilling or overfilling of THVs is safe and feasible, conforming to the original annulus and covering a continuous range of annular sizes with limited THV size options. However, care should be taken when underfilling 23-mm THVs due to the potential for increased transvalvular gradient.
KW - Aortic stenosis
KW - Multidetector computed tomography
KW - Overfilling
KW - Transcatheter aortic valve implantation
KW - Underfilling
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UR - http://www.scopus.com/inward/citedby.url?scp=84981169964&partnerID=8YFLogxK
U2 - 10.1016/j.ijcard.2016.07.218
DO - 10.1016/j.ijcard.2016.07.218
M3 - Article
C2 - 27521550
AN - SCOPUS:84981169964
VL - 222
SP - 738
EP - 744
JO - International Journal of Cardiology
JF - International Journal of Cardiology
SN - 0167-5273
ER -