Impaired decision-making in Parkinson's disease

Masaru Mimura; Reiko Oeda; Mitsuru Kawamura

doi:10.1016/j.parkreldis.2005.12.003

Impaired decision-making in Parkinson's disease

Masaru Mimura, Reiko Oeda, Mitsuru Kawamura

Research output: Contribution to journal › Article › peer-review

161 Citations (Scopus)

Abstract

The present study demonstrated that individuals with Parkinson's disease display impairments in making profitable decisions, as evidenced by poorer performance on the Iowa Gambling Task relative to matched controls. The ability to make beneficial judgments solely correlates with ability to appropriately attribute internal mental-state to other people, as shown in a mind-reading task. However, decision-making ability for individuals with Parkinson's disease is not associated with effective execution, intellectual function or depressed mood. These findings offer a new perspective on the cognitive impairments that affect social living and adaptive decisions for individuals with Parkinson's disease.

Original language	English
Pages (from-to)	169-175
Number of pages	7
Journal	Parkinsonism and Related Disorders
Volume	12
Issue number	3
DOIs	https://doi.org/10.1016/j.parkreldis.2005.12.003
Publication status	Published - 2006 Apr
Externally published	Yes

Keywords

Decision-making
Executive function
Mind-reading
Parkinson's disease
Social cognition

ASJC Scopus subject areas

Neurology
Geriatrics and Gerontology
Clinical Neurology

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10.1016/j.parkreldis.2005.12.003

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title = "Impaired decision-making in Parkinson's disease",

abstract = "The present study demonstrated that individuals with Parkinson's disease display impairments in making profitable decisions, as evidenced by poorer performance on the Iowa Gambling Task relative to matched controls. The ability to make beneficial judgments solely correlates with ability to appropriately attribute internal mental-state to other people, as shown in a mind-reading task. However, decision-making ability for individuals with Parkinson's disease is not associated with effective execution, intellectual function or depressed mood. These findings offer a new perspective on the cognitive impairments that affect social living and adaptive decisions for individuals with Parkinson's disease.",

keywords = "Decision-making, Executive function, Mind-reading, Parkinson's disease, Social cognition",

author = "Masaru Mimura and Reiko Oeda and Mitsuru Kawamura",

note = "Funding Information: This work was supported by a Grant-in-Aid for Scientific Research on Priority Areas (b) -Advanced Brain Science Project- from Ministry of Education, Culture, Sports, and Science and Technology, Japan (M.M). M.K. was supported by CREST, and the Grant-in-Aid for Scientific Research on Priority Areas-System study on higher-order brain functions from MEXT (17022035). This study was also supported in part by a showa University Grant-in-Aid for Innovative Collaborative Research Projects (M.M., M.K.). The authors thank Drs K. Tanaka and S. Koyama for their helpful comments on statistical analyses.",

year = "2006",

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doi = "10.1016/j.parkreldis.2005.12.003",

language = "English",

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pages = "169--175",

journal = "Parkinsonism and Related Disorders",

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T1 - Impaired decision-making in Parkinson's disease

AU - Mimura, Masaru

AU - Oeda, Reiko

AU - Kawamura, Mitsuru

N1 - Funding Information: This work was supported by a Grant-in-Aid for Scientific Research on Priority Areas (b) -Advanced Brain Science Project- from Ministry of Education, Culture, Sports, and Science and Technology, Japan (M.M). M.K. was supported by CREST, and the Grant-in-Aid for Scientific Research on Priority Areas-System study on higher-order brain functions from MEXT (17022035). This study was also supported in part by a showa University Grant-in-Aid for Innovative Collaborative Research Projects (M.M., M.K.). The authors thank Drs K. Tanaka and S. Koyama for their helpful comments on statistical analyses.

PY - 2006/4

Y1 - 2006/4

N2 - The present study demonstrated that individuals with Parkinson's disease display impairments in making profitable decisions, as evidenced by poorer performance on the Iowa Gambling Task relative to matched controls. The ability to make beneficial judgments solely correlates with ability to appropriately attribute internal mental-state to other people, as shown in a mind-reading task. However, decision-making ability for individuals with Parkinson's disease is not associated with effective execution, intellectual function or depressed mood. These findings offer a new perspective on the cognitive impairments that affect social living and adaptive decisions for individuals with Parkinson's disease.

AB - The present study demonstrated that individuals with Parkinson's disease display impairments in making profitable decisions, as evidenced by poorer performance on the Iowa Gambling Task relative to matched controls. The ability to make beneficial judgments solely correlates with ability to appropriately attribute internal mental-state to other people, as shown in a mind-reading task. However, decision-making ability for individuals with Parkinson's disease is not associated with effective execution, intellectual function or depressed mood. These findings offer a new perspective on the cognitive impairments that affect social living and adaptive decisions for individuals with Parkinson's disease.

KW - Decision-making

KW - Executive function

KW - Mind-reading

KW - Parkinson's disease

KW - Social cognition

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JO - Parkinsonism and Related Disorders

JF - Parkinsonism and Related Disorders

IS - 3

ER -

Impaired decision-making in Parkinson's disease

Abstract

Keywords

ASJC Scopus subject areas

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