Implication of augmented vasogenic leakage in the mechanism of persistent aura in sporadic hemiplegic migraine

T. Iizuka, F. Sakai, K. Suzuki, H. Igarashi, N. Suzuki

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

The aim of this study is to report a possible implication of augmented vasogenic leakage in the mechanism of prolonged aura in sporadic hemiplegic migraine. A 35-year-old woman with sporadic hemiplegic migraine presented with headache followed by right arm weakness, right visual field defect, aphasia and confusion that persisted for 1 week. During the acute stage, focal hyperaemia was seen in the left cerebral hemisphere corresponding to persistent aura symptoms. Augmented vasogenic leakage was demonstrated on delayed enhanced fluid-attenuated inversion recovery image. Magnetic resonance angiography showed dilation of the left middle cerebral artery. During the convalescent stage, such abnormal findings were not seen. Based on these results, we speculate that augmented vasogenic leakage from the leptomeningeal vessels, probably associated with activation of the trigeminovascular system, may delay the recovery of hemiplegic migraine aura.

Original languageEnglish
Pages (from-to)332-335
Number of pages4
JournalCephalalgia
Volume26
Issue number3
DOIs
Publication statusPublished - 2006 Mar

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Epilepsy
Confusion
Magnetic Resonance Angiography
Aphasia
Hyperemia
Middle Cerebral Artery
Cerebrum
Visual Fields
Migraine Disorders
Headache
Dilatation
Sporadic Hemiplegic Migraine

Keywords

  • Hyperaemia
  • Persistent aura
  • Sporadic hemiplegic migraine
  • Vasogenic leakage

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Implication of augmented vasogenic leakage in the mechanism of persistent aura in sporadic hemiplegic migraine. / Iizuka, T.; Sakai, F.; Suzuki, K.; Igarashi, H.; Suzuki, N.

In: Cephalalgia, Vol. 26, No. 3, 03.2006, p. 332-335.

Research output: Contribution to journalArticle

Iizuka, T. ; Sakai, F. ; Suzuki, K. ; Igarashi, H. ; Suzuki, N. / Implication of augmented vasogenic leakage in the mechanism of persistent aura in sporadic hemiplegic migraine. In: Cephalalgia. 2006 ; Vol. 26, No. 3. pp. 332-335.
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