Importance of skin perfusion pressure in treatment of critical limb ischemiai

Yoriko Tsuji, Terashi Hiroto, Ikuro Kitano, Shinya Tahara, Daisuke Sugiyama

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

The authors studied whether skin perfusion pressure (SPP) measurements can be used to accurately predict wound healing in critical limb ischemia (CLI) and to select peripheral arterial reconstructive procedures. Methods. Forty-seven patients (33 men and 14 women, age 36ĝ€"83 years) with 69 ischemic limbs with foot ulcers or gangrene were studied retrospectively. Skin perfusion pressure was compared to the treatment outcomes (ulcers healed and ulcers that failed to heal). As a diagnostic test for CLI, the sensitivity, specificity, and the positive and the negative predictive values (PPV, NPV) of SPP measurement were calculated; the data was then analyzed by the receiver operation characteristic (ROC) curve. Results. According to the ROC curve, the best SPP measurement performance was at 35 mmHg. Conclusion. Wound healing at the appropriate amputation level must be predicted to minimize invasive debridement. Skin perfusion pressure measurement is useful for predicting wound healing in the presence of CLI. Skin perfusion pressure ĝ‰¥ 35 mmHg is requisite for wound healing; at SPP

Original languageEnglish
Pages (from-to)95-100
Number of pages6
JournalWounds
Volume20
Issue number4
Publication statusPublished - 2008 Apr
Externally publishedYes

Fingerprint

Extremities
Perfusion
Pressure
Skin
Wound Healing
Ischemia
Therapeutics
Ulcer
Foot Ulcer
Gangrene
Debridement
Amputation
Routine Diagnostic Tests
Sensitivity and Specificity

Keywords

  • Autolytic debridement
  • Compression stockings
  • Delayed wound healing
  • Diabetic foot wounds
  • Impaired wound healing
  • Mechanical debridement
  • Pressure dressing
  • Surgical debridement
  • Wound fibroblasts
  • Wound necrosis

ASJC Scopus subject areas

  • Surgery

Cite this

Tsuji, Y., Hiroto, T., Kitano, I., Tahara, S., & Sugiyama, D. (2008). Importance of skin perfusion pressure in treatment of critical limb ischemiai. Wounds, 20(4), 95-100.

Importance of skin perfusion pressure in treatment of critical limb ischemiai. / Tsuji, Yoriko; Hiroto, Terashi; Kitano, Ikuro; Tahara, Shinya; Sugiyama, Daisuke.

In: Wounds, Vol. 20, No. 4, 04.2008, p. 95-100.

Research output: Contribution to journalArticle

Tsuji, Y, Hiroto, T, Kitano, I, Tahara, S & Sugiyama, D 2008, 'Importance of skin perfusion pressure in treatment of critical limb ischemiai', Wounds, vol. 20, no. 4, pp. 95-100.
Tsuji Y, Hiroto T, Kitano I, Tahara S, Sugiyama D. Importance of skin perfusion pressure in treatment of critical limb ischemiai. Wounds. 2008 Apr;20(4):95-100.
Tsuji, Yoriko ; Hiroto, Terashi ; Kitano, Ikuro ; Tahara, Shinya ; Sugiyama, Daisuke. / Importance of skin perfusion pressure in treatment of critical limb ischemiai. In: Wounds. 2008 ; Vol. 20, No. 4. pp. 95-100.
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