Improvements in French risk stratification score were correlated with reductions in mean pulmonary artery pressure in pulmonary arterial hypertension: a subanalysis of the Japan Pulmonary Hypertension Registry (JAPHR)

the Japan Pulmonary Hypertension Registry (JAPHR) Network

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Abstract

Background: Since there was no previous report, we analyzed the relationship between French Risk Stratification parameters in pulmonary arterial hypertension (PAH) and mean pulmonary arterial pressures (mPAP) using Japan PH Registry (JAPHR) national-wide cohort. Methods: We enrolled 108 patients with PAH from JAPHR from previous reported cohort and analyzed the relations between French Risk Stratification scores and hemodynamic improvements. Results: The ratio meeting 0 to 4 French Risk Stratification score was 21.3%, 31.5%, 32.4%, 13.0%, and 1.9% at baseline, and 6.5%, 23.2%, 33.3%, 23.2%, 13.9% at follow-up, respectively. The improvements in the number of criteria met were associated both with mPAP at follow-up (p = 0.03) and with the improvements in mPAP (p < 0.001). Conclusion: The improvements in French Risk Stratification may become a marker of improved hemodynamics including mPAP.

Original languageEnglish
Article number28
JournalBMC Pulmonary Medicine
Volume21
Issue number1
DOIs
Publication statusPublished - 2021 Dec

Keywords

  • Mean pulmonary arterial pressures
  • Pulmonary arterial hypertension
  • Registry
  • Risk stratification

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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