Abstract
The translation system in a cell is a powerful molecular machine conducted by ribosomes, tRNAs, and several translation factors to synthesize proteins. The translation process is very accurate according to the genetic code and directed from 5′-end to 3′-end on messenger RNA. We employ the translation mechanism combined with four-base codon techniques to develop a molecular machine which computes finite automata (finite-state machine). We report some experimental results where we have succeeded to implement a finite automaton on an E. coli in vitro translation system with four-base codons.
| Original language | English |
|---|---|
| Pages (from-to) | 197-202 |
| Number of pages | 6 |
| Journal | Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) |
| Volume | 2943 |
| Publication status | Published - 2004 |
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ASJC Scopus subject areas
- Computer Science(all)
- Biochemistry, Genetics and Molecular Biology(all)
- Theoretical Computer Science
Cite this
In vitro translation-based computations. / Sakakibara, Yasubumi; Hohsaka, Takahiro.
In: Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), Vol. 2943, 2004, p. 197-202.Research output: Contribution to journal › Article
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TY - JOUR
T1 - In vitro translation-based computations
AU - Sakakibara, Yasubumi
AU - Hohsaka, Takahiro
PY - 2004
Y1 - 2004
N2 - The translation system in a cell is a powerful molecular machine conducted by ribosomes, tRNAs, and several translation factors to synthesize proteins. The translation process is very accurate according to the genetic code and directed from 5′-end to 3′-end on messenger RNA. We employ the translation mechanism combined with four-base codon techniques to develop a molecular machine which computes finite automata (finite-state machine). We report some experimental results where we have succeeded to implement a finite automaton on an E. coli in vitro translation system with four-base codons.
AB - The translation system in a cell is a powerful molecular machine conducted by ribosomes, tRNAs, and several translation factors to synthesize proteins. The translation process is very accurate according to the genetic code and directed from 5′-end to 3′-end on messenger RNA. We employ the translation mechanism combined with four-base codon techniques to develop a molecular machine which computes finite automata (finite-state machine). We report some experimental results where we have succeeded to implement a finite automaton on an E. coli in vitro translation system with four-base codons.
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UR - http://www.scopus.com/inward/citedby.url?scp=35048825335&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:35048825335
VL - 2943
SP - 197
EP - 202
JO - Lecture Notes in Computer Science
JF - Lecture Notes in Computer Science
SN - 0302-9743
ER -