In vitro translation-based computations

Yasubumi Sakakibara, Takahiro Hohsaka

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The translation system in a cell is a powerful molecular machine conducted by ribosomes, tRNAs, and several translation factors to synthesize proteins. The translation process is very accurate according to the genetic code and directed from 5′-end to 3′-end on messenger RNA. We employ the translation mechanism combined with four-base codon techniques to develop a molecular machine which computes finite automata (finite-state machine). We report some experimental results where we have succeeded to implement a finite automaton on an E. coli in vitro translation system with four-base codons.

Original languageEnglish
Pages (from-to)197-202
Number of pages6
JournalLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume2943
Publication statusPublished - 2004

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Finite automata
Codon
Genetic Code
Transfer RNA
Ribosomes
Finite Automata
Escherichia coli
Messenger RNA
Proteins
State Machine
Escherichia Coli
In Vitro Techniques
Protein
Cell
Experimental Results

ASJC Scopus subject areas

  • Computer Science(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Theoretical Computer Science

Cite this

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