In vivo evaluation of corneal epithelium seeded PVA hydrogel as an artificial corneal stroma

Hisatoshi Kobayashi, Masabumi Kato, Tetsushi Taguchi, Shigeto Shimmura, Hideyuki Miyashita, Kazuo Tsubota, Junzo Tanaka

Research output: Contribution to conferencePaper

1 Citation (Scopus)

Abstract

We have reported the transparent poly(vinyl alcohol) hydrogel with type I collagen covalently immobilized had a good affinity toward rabbit corneal epithelium. In this study, we evaluated the in vivo stability of the pre-seeded corneal epithelium on the PVA-COL. Corneal epithelium was stratification on the PVA-Col in vitro culture and the epithelium pre-seeded PVA-COL was implanted in the rabbit cornea and evaluated the in vivo stability. The pre-seeded epithelium layer was peeled off within a week. Improvement of the in vivo stability was required.

Original languageEnglish
Number of pages1
Publication statusPublished - 2005 Dec 1
Event54th SPSJ Annual Meeting 2005 - Yokohama, Japan
Duration: 2005 May 252005 May 27

Other

Other54th SPSJ Annual Meeting 2005
CountryJapan
CityYokohama
Period05/5/2505/5/27

Keywords

  • Artificial cornea
  • Epithelium
  • In vivo
  • Pre-seeded
  • PVA hydrogel

ASJC Scopus subject areas

  • Engineering(all)

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  • Cite this

    Kobayashi, H., Kato, M., Taguchi, T., Shimmura, S., Miyashita, H., Tsubota, K., & Tanaka, J. (2005). In vivo evaluation of corneal epithelium seeded PVA hydrogel as an artificial corneal stroma. Paper presented at 54th SPSJ Annual Meeting 2005, Yokohama, Japan.