In vivo evaluation of corneal epithelium seeded PVA hydrogel as an artificial corneal stroma

Hisatoshi Kobayashi, Masabumi Kato, Tetsushi Taguchi, Shigeto Shimmura, Hideyuki Miyashita, Kazuo Tsubota, Junzo Tanaka

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

We have reported the transparent poly(vinyl alcohol) hydrogel with type I collagen covalently immobilized had a good affinity toward rabbit corneal epithelium. In this study, we evaluated the in vivo stability of the pre-seeded corneal epithelium on the PVA-COL. Corneal epithelium was stratification on the PVA-Col in vitro culture and the epithelium pre-seeded PVA-COL was implanted in the rabbit cornea and evaluated the in vivo stability. The pre-seeded epithelium layer was peeled off within a week. Improvement of the in vivo stability was required.

Original languageEnglish
Title of host publicationPolymer Preprints, Japan
Pages2247
Number of pages1
Volume54
Edition1
Publication statusPublished - 2005
Event54th SPSJ Annual Meeting 2005 - Yokohama, Japan
Duration: 2005 May 252005 May 27

Other

Other54th SPSJ Annual Meeting 2005
CountryJapan
CityYokohama
Period05/5/2505/5/27

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Hydrogels
Collagen
Alcohols

Keywords

  • Artificial cornea
  • Epithelium
  • In vivo
  • Pre-seeded
  • PVA hydrogel

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Kobayashi, H., Kato, M., Taguchi, T., Shimmura, S., Miyashita, H., Tsubota, K., & Tanaka, J. (2005). In vivo evaluation of corneal epithelium seeded PVA hydrogel as an artificial corneal stroma. In Polymer Preprints, Japan (1 ed., Vol. 54, pp. 2247)

In vivo evaluation of corneal epithelium seeded PVA hydrogel as an artificial corneal stroma. / Kobayashi, Hisatoshi; Kato, Masabumi; Taguchi, Tetsushi; Shimmura, Shigeto; Miyashita, Hideyuki; Tsubota, Kazuo; Tanaka, Junzo.

Polymer Preprints, Japan. Vol. 54 1. ed. 2005. p. 2247.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Kobayashi, H, Kato, M, Taguchi, T, Shimmura, S, Miyashita, H, Tsubota, K & Tanaka, J 2005, In vivo evaluation of corneal epithelium seeded PVA hydrogel as an artificial corneal stroma. in Polymer Preprints, Japan. 1 edn, vol. 54, pp. 2247, 54th SPSJ Annual Meeting 2005, Yokohama, Japan, 05/5/25.
Kobayashi H, Kato M, Taguchi T, Shimmura S, Miyashita H, Tsubota K et al. In vivo evaluation of corneal epithelium seeded PVA hydrogel as an artificial corneal stroma. In Polymer Preprints, Japan. 1 ed. Vol. 54. 2005. p. 2247
Kobayashi, Hisatoshi ; Kato, Masabumi ; Taguchi, Tetsushi ; Shimmura, Shigeto ; Miyashita, Hideyuki ; Tsubota, Kazuo ; Tanaka, Junzo. / In vivo evaluation of corneal epithelium seeded PVA hydrogel as an artificial corneal stroma. Polymer Preprints, Japan. Vol. 54 1. ed. 2005. pp. 2247
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