In vivo evaluation of corneal epithelium seeded PVA hydrogel as an artificial corneal stroma

Hisatoshi Kobayashi; Masabumi Kato; Tetsushi Taguchi; Shigeto Shimmura; Hideyuki Miyashita; Kazuo Tsubota; Junzo Tanaka

In vivo evaluation of corneal epithelium seeded PVA hydrogel as an artificial corneal stroma

Hisatoshi Kobayashi, Masabumi Kato, Tetsushi Taguchi, Shigeto Shimmura, Hideyuki Miyashita, Kazuo Tsubota, Junzo Tanaka

Department of Ophthalmology

Research output: Contribution to conference › Paper › peer-review

1 Citation (Scopus)

Abstract

We have reported the transparent poly(vinyl alcohol) hydrogel with type I collagen covalently immobilized had a good affinity toward rabbit corneal epithelium. In this study, we evaluated the in vivo stability of the pre-seeded corneal epithelium on the PVA-COL. Corneal epithelium was stratification on the PVA-Col in vitro culture and the epithelium pre-seeded PVA-COL was implanted in the rabbit cornea and evaluated the in vivo stability. The pre-seeded epithelium layer was peeled off within a week. Improvement of the in vivo stability was required.

Original language	English
Number of pages	1
Publication status	Published - 2005 Dec 1
Event	54th SPSJ Annual Meeting 2005 - Yokohama, Japan Duration: 2005 May 25 → 2005 May 27

Other

Other	54th SPSJ Annual Meeting 2005
Country/Territory	Japan
City	Yokohama
Period	05/5/25 → 05/5/27

Keywords

Artificial cornea
Epithelium
In vivo
Pre-seeded
PVA hydrogel

ASJC Scopus subject areas

Engineering(all)

Cite this

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title = "In vivo evaluation of corneal epithelium seeded PVA hydrogel as an artificial corneal stroma",

abstract = "We have reported the transparent poly(vinyl alcohol) hydrogel with type I collagen covalently immobilized had a good affinity toward rabbit corneal epithelium. In this study, we evaluated the in vivo stability of the pre-seeded corneal epithelium on the PVA-COL. Corneal epithelium was stratification on the PVA-Col in vitro culture and the epithelium pre-seeded PVA-COL was implanted in the rabbit cornea and evaluated the in vivo stability. The pre-seeded epithelium layer was peeled off within a week. Improvement of the in vivo stability was required.",

keywords = "Artificial cornea, Epithelium, In vivo, Pre-seeded, PVA hydrogel",

author = "Hisatoshi Kobayashi and Masabumi Kato and Tetsushi Taguchi and Shigeto Shimmura and Hideyuki Miyashita and Kazuo Tsubota and Junzo Tanaka",

year = "2005",

month = dec,

day = "1",

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note = "54th SPSJ Annual Meeting 2005 ; Conference date: 25-05-2005 Through 27-05-2005",

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TY - CONF

T1 - In vivo evaluation of corneal epithelium seeded PVA hydrogel as an artificial corneal stroma

AU - Kobayashi, Hisatoshi

AU - Kato, Masabumi

AU - Taguchi, Tetsushi

AU - Shimmura, Shigeto

AU - Miyashita, Hideyuki

AU - Tsubota, Kazuo

AU - Tanaka, Junzo

PY - 2005/12/1

Y1 - 2005/12/1

N2 - We have reported the transparent poly(vinyl alcohol) hydrogel with type I collagen covalently immobilized had a good affinity toward rabbit corneal epithelium. In this study, we evaluated the in vivo stability of the pre-seeded corneal epithelium on the PVA-COL. Corneal epithelium was stratification on the PVA-Col in vitro culture and the epithelium pre-seeded PVA-COL was implanted in the rabbit cornea and evaluated the in vivo stability. The pre-seeded epithelium layer was peeled off within a week. Improvement of the in vivo stability was required.

AB - We have reported the transparent poly(vinyl alcohol) hydrogel with type I collagen covalently immobilized had a good affinity toward rabbit corneal epithelium. In this study, we evaluated the in vivo stability of the pre-seeded corneal epithelium on the PVA-COL. Corneal epithelium was stratification on the PVA-Col in vitro culture and the epithelium pre-seeded PVA-COL was implanted in the rabbit cornea and evaluated the in vivo stability. The pre-seeded epithelium layer was peeled off within a week. Improvement of the in vivo stability was required.

KW - Artificial cornea

KW - Epithelium

KW - In vivo

KW - Pre-seeded

KW - PVA hydrogel

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M3 - Paper

AN - SCOPUS:33645646765

T2 - 54th SPSJ Annual Meeting 2005

Y2 - 25 May 2005 through 27 May 2005

ER -

In vivo evaluation of corneal epithelium seeded PVA hydrogel as an artificial corneal stroma

Abstract

Other

Keywords

ASJC Scopus subject areas

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