TY - JOUR
T1 - Inactivation of nontuberculous mycobacteria by gaseous ozone treatment
AU - Misawa, Kana
AU - Nishimura, Tomoyasu
AU - Kashimura, Shoko
AU - Hasegawa, Naoki
N1 - Funding Information:
We thank Tamura TECO Co. Ltd. (Higashiosaka-shi, Osaka, Japan) for technical assistance.
Publisher Copyright:
© 2023 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control
PY - 2023/6
Y1 - 2023/6
N2 - Nontuberculous mycobacteria (NTM) are environmental bacteria resistant to many common disinfectants and ultraviolet radiation. Inhalation of aerosols generated from NTM-containing water and soil causes NTM lung disease, especially in people with underlying lung diseases and decreased immunity. To prevent healthcare-acquired NTM infections, it is important to eradicate NTM living in hospital environments. Therefore, we evaluated the efficacy of gaseous ozone for the inactivation of NTM, namely Mycobacterium (M.) avium, M. intracellulare, M. kansasii, M. abscessus subsp. abscessus and M. abscessus subsp. massiliense. Gaseous ozone treatment at 1 ppm for 3 h reduced the bacterial number of all strains by more than 97%. Gaseous ozone treatment could be a practical, effective and convenient disinfection method for NTM living in hospital environments.
AB - Nontuberculous mycobacteria (NTM) are environmental bacteria resistant to many common disinfectants and ultraviolet radiation. Inhalation of aerosols generated from NTM-containing water and soil causes NTM lung disease, especially in people with underlying lung diseases and decreased immunity. To prevent healthcare-acquired NTM infections, it is important to eradicate NTM living in hospital environments. Therefore, we evaluated the efficacy of gaseous ozone for the inactivation of NTM, namely Mycobacterium (M.) avium, M. intracellulare, M. kansasii, M. abscessus subsp. abscessus and M. abscessus subsp. massiliense. Gaseous ozone treatment at 1 ppm for 3 h reduced the bacterial number of all strains by more than 97%. Gaseous ozone treatment could be a practical, effective and convenient disinfection method for NTM living in hospital environments.
KW - Disinfection
KW - Gaseous ozone
KW - Nontuberculous mycobacteria
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U2 - 10.1016/j.jiac.2023.03.004
DO - 10.1016/j.jiac.2023.03.004
M3 - Article
C2 - 36894014
AN - SCOPUS:85150780302
SN - 1341-321X
VL - 29
SP - 628
EP - 630
JO - Journal of Infection and Chemotherapy
JF - Journal of Infection and Chemotherapy
IS - 6
ER -
