Incidence and risk factors for postoperative delirium after major head and neck cancer surgery

Eisuke Booka, Tomoyuki Kamijo, Teruaki Matsumoto, Mari Takeuchi, Takashi Kitani, Masato Nagaoka, Atsushi Imai, Yoshiyuki Iida, Ayako Shimada, Katsushi Takebayashi, Masahiro Niihara, Keita Mori, Tetsuro Onitsuka, Yasuhiro Tsubosa, Hiroya Takeuchi, Yuukou Kitagawa

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9 Citations (Scopus)

Abstract

Background Postoperative delirium is a common and serious complication after extensive surgery. This study aimed to investigate the incidence and risk factors for postoperative delirium after major head and neck cancer surgery. Methods A retrospective analysis was performed for 293 patients who underwent major head and neck cancer surgery lasting >6 h at our institution between January 2012 and November 2015. All data were assessed by two psychiatrists. Univariate and multivariate analyses were performed. Results Postoperative delirium developed in 50 (17.1%) patients; most cases (84.0%) of postoperative delirium were observed between postoperative day (POD) 1 and POD 3. Multivariate analysis revealed that an age >70 years was the significant risk factor for postoperative delirium incidence after major head and neck cancer surgery; the multivariate hazard ratio was 3.935 (95% confidence interval 1.873-8.265, p <0.001). Conclusions Most cases of postoperative delirium after major head and neck cancer surgery were observed between POD 1 and POD 3, and a multivariate analysis revealed that an age >70 years was a significant risk factor for postoperative delirium incidence. Clinicians should pay particular attention to the possibility of delirium incidence during the first 3 days after surgery for patients aged >70 years.

Original languageEnglish
Pages (from-to)890-894
Number of pages5
JournalJournal of Cranio-Maxillofacial Surgery
Volume44
Issue number7
DOIs
Publication statusPublished - 2016 Jul 1

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Keywords

  • Head and neck cancer
  • Older age
  • Postoperative delirium

ASJC Scopus subject areas

  • Oral Surgery
  • Otorhinolaryngology
  • Surgery

Cite this

Booka, E., Kamijo, T., Matsumoto, T., Takeuchi, M., Kitani, T., Nagaoka, M., Imai, A., Iida, Y., Shimada, A., Takebayashi, K., Niihara, M., Mori, K., Onitsuka, T., Tsubosa, Y., Takeuchi, H., & Kitagawa, Y. (2016). Incidence and risk factors for postoperative delirium after major head and neck cancer surgery. Journal of Cranio-Maxillofacial Surgery, 44(7), 890-894. https://doi.org/10.1016/j.jcms.2016.04.032