Incidence and risk factors for postoperative delirium after major head and neck cancer surgery

Eisuke Booka, Tomoyuki Kamijo, Teruaki Matsumoto, Mari Takeuchi, Takashi Kitani, Masato Nagaoka, Atsushi Imai, Yoshiyuki Iida, Ayako Shimada, Katsushi Takebayashi, Masahiro Niihara, Keita Mori, Tetsuro Onitsuka, Yasuhiro Tsubosa, Hiroya Takeuchi, Yuukou Kitagawa

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Background Postoperative delirium is a common and serious complication after extensive surgery. This study aimed to investigate the incidence and risk factors for postoperative delirium after major head and neck cancer surgery. Methods A retrospective analysis was performed for 293 patients who underwent major head and neck cancer surgery lasting >6 h at our institution between January 2012 and November 2015. All data were assessed by two psychiatrists. Univariate and multivariate analyses were performed. Results Postoperative delirium developed in 50 (17.1%) patients; most cases (84.0%) of postoperative delirium were observed between postoperative day (POD) 1 and POD 3. Multivariate analysis revealed that an age >70 years was the significant risk factor for postoperative delirium incidence after major head and neck cancer surgery; the multivariate hazard ratio was 3.935 (95% confidence interval 1.873-8.265, p <0.001). Conclusions Most cases of postoperative delirium after major head and neck cancer surgery were observed between POD 1 and POD 3, and a multivariate analysis revealed that an age >70 years was a significant risk factor for postoperative delirium incidence. Clinicians should pay particular attention to the possibility of delirium incidence during the first 3 days after surgery for patients aged >70 years.

Original languageEnglish
Pages (from-to)890-894
Number of pages5
JournalJournal of Cranio-Maxillofacial Surgery
Volume44
Issue number7
DOIs
Publication statusPublished - 2016 Jul 1

Fingerprint

Delirium
Head and Neck Neoplasms
Incidence
Multivariate Analysis
Ambulatory Surgical Procedures
Psychiatry
Confidence Intervals

Keywords

  • Head and neck cancer
  • Older age
  • Postoperative delirium

ASJC Scopus subject areas

  • Oral Surgery
  • Otorhinolaryngology
  • Surgery

Cite this

Incidence and risk factors for postoperative delirium after major head and neck cancer surgery. / Booka, Eisuke; Kamijo, Tomoyuki; Matsumoto, Teruaki; Takeuchi, Mari; Kitani, Takashi; Nagaoka, Masato; Imai, Atsushi; Iida, Yoshiyuki; Shimada, Ayako; Takebayashi, Katsushi; Niihara, Masahiro; Mori, Keita; Onitsuka, Tetsuro; Tsubosa, Yasuhiro; Takeuchi, Hiroya; Kitagawa, Yuukou.

In: Journal of Cranio-Maxillofacial Surgery, Vol. 44, No. 7, 01.07.2016, p. 890-894.

Research output: Contribution to journalArticle

Booka, E, Kamijo, T, Matsumoto, T, Takeuchi, M, Kitani, T, Nagaoka, M, Imai, A, Iida, Y, Shimada, A, Takebayashi, K, Niihara, M, Mori, K, Onitsuka, T, Tsubosa, Y, Takeuchi, H & Kitagawa, Y 2016, 'Incidence and risk factors for postoperative delirium after major head and neck cancer surgery', Journal of Cranio-Maxillofacial Surgery, vol. 44, no. 7, pp. 890-894. https://doi.org/10.1016/j.jcms.2016.04.032
Booka, Eisuke ; Kamijo, Tomoyuki ; Matsumoto, Teruaki ; Takeuchi, Mari ; Kitani, Takashi ; Nagaoka, Masato ; Imai, Atsushi ; Iida, Yoshiyuki ; Shimada, Ayako ; Takebayashi, Katsushi ; Niihara, Masahiro ; Mori, Keita ; Onitsuka, Tetsuro ; Tsubosa, Yasuhiro ; Takeuchi, Hiroya ; Kitagawa, Yuukou. / Incidence and risk factors for postoperative delirium after major head and neck cancer surgery. In: Journal of Cranio-Maxillofacial Surgery. 2016 ; Vol. 44, No. 7. pp. 890-894.
@article{4bfabc201f4d4329bce14a3cac4a6bc1,
title = "Incidence and risk factors for postoperative delirium after major head and neck cancer surgery",
abstract = "Background Postoperative delirium is a common and serious complication after extensive surgery. This study aimed to investigate the incidence and risk factors for postoperative delirium after major head and neck cancer surgery. Methods A retrospective analysis was performed for 293 patients who underwent major head and neck cancer surgery lasting >6 h at our institution between January 2012 and November 2015. All data were assessed by two psychiatrists. Univariate and multivariate analyses were performed. Results Postoperative delirium developed in 50 (17.1{\%}) patients; most cases (84.0{\%}) of postoperative delirium were observed between postoperative day (POD) 1 and POD 3. Multivariate analysis revealed that an age >70 years was the significant risk factor for postoperative delirium incidence after major head and neck cancer surgery; the multivariate hazard ratio was 3.935 (95{\%} confidence interval 1.873-8.265, p <0.001). Conclusions Most cases of postoperative delirium after major head and neck cancer surgery were observed between POD 1 and POD 3, and a multivariate analysis revealed that an age >70 years was a significant risk factor for postoperative delirium incidence. Clinicians should pay particular attention to the possibility of delirium incidence during the first 3 days after surgery for patients aged >70 years.",
keywords = "Head and neck cancer, Older age, Postoperative delirium",
author = "Eisuke Booka and Tomoyuki Kamijo and Teruaki Matsumoto and Mari Takeuchi and Takashi Kitani and Masato Nagaoka and Atsushi Imai and Yoshiyuki Iida and Ayako Shimada and Katsushi Takebayashi and Masahiro Niihara and Keita Mori and Tetsuro Onitsuka and Yasuhiro Tsubosa and Hiroya Takeuchi and Yuukou Kitagawa",
year = "2016",
month = "7",
day = "1",
doi = "10.1016/j.jcms.2016.04.032",
language = "English",
volume = "44",
pages = "890--894",
journal = "Journal of Cranio-Maxillofacial Surgery",
issn = "1010-5182",
publisher = "Churchill Livingstone",
number = "7",

}

TY - JOUR

T1 - Incidence and risk factors for postoperative delirium after major head and neck cancer surgery

AU - Booka, Eisuke

AU - Kamijo, Tomoyuki

AU - Matsumoto, Teruaki

AU - Takeuchi, Mari

AU - Kitani, Takashi

AU - Nagaoka, Masato

AU - Imai, Atsushi

AU - Iida, Yoshiyuki

AU - Shimada, Ayako

AU - Takebayashi, Katsushi

AU - Niihara, Masahiro

AU - Mori, Keita

AU - Onitsuka, Tetsuro

AU - Tsubosa, Yasuhiro

AU - Takeuchi, Hiroya

AU - Kitagawa, Yuukou

PY - 2016/7/1

Y1 - 2016/7/1

N2 - Background Postoperative delirium is a common and serious complication after extensive surgery. This study aimed to investigate the incidence and risk factors for postoperative delirium after major head and neck cancer surgery. Methods A retrospective analysis was performed for 293 patients who underwent major head and neck cancer surgery lasting >6 h at our institution between January 2012 and November 2015. All data were assessed by two psychiatrists. Univariate and multivariate analyses were performed. Results Postoperative delirium developed in 50 (17.1%) patients; most cases (84.0%) of postoperative delirium were observed between postoperative day (POD) 1 and POD 3. Multivariate analysis revealed that an age >70 years was the significant risk factor for postoperative delirium incidence after major head and neck cancer surgery; the multivariate hazard ratio was 3.935 (95% confidence interval 1.873-8.265, p <0.001). Conclusions Most cases of postoperative delirium after major head and neck cancer surgery were observed between POD 1 and POD 3, and a multivariate analysis revealed that an age >70 years was a significant risk factor for postoperative delirium incidence. Clinicians should pay particular attention to the possibility of delirium incidence during the first 3 days after surgery for patients aged >70 years.

AB - Background Postoperative delirium is a common and serious complication after extensive surgery. This study aimed to investigate the incidence and risk factors for postoperative delirium after major head and neck cancer surgery. Methods A retrospective analysis was performed for 293 patients who underwent major head and neck cancer surgery lasting >6 h at our institution between January 2012 and November 2015. All data were assessed by two psychiatrists. Univariate and multivariate analyses were performed. Results Postoperative delirium developed in 50 (17.1%) patients; most cases (84.0%) of postoperative delirium were observed between postoperative day (POD) 1 and POD 3. Multivariate analysis revealed that an age >70 years was the significant risk factor for postoperative delirium incidence after major head and neck cancer surgery; the multivariate hazard ratio was 3.935 (95% confidence interval 1.873-8.265, p <0.001). Conclusions Most cases of postoperative delirium after major head and neck cancer surgery were observed between POD 1 and POD 3, and a multivariate analysis revealed that an age >70 years was a significant risk factor for postoperative delirium incidence. Clinicians should pay particular attention to the possibility of delirium incidence during the first 3 days after surgery for patients aged >70 years.

KW - Head and neck cancer

KW - Older age

KW - Postoperative delirium

UR - http://www.scopus.com/inward/record.url?scp=84971619628&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84971619628&partnerID=8YFLogxK

U2 - 10.1016/j.jcms.2016.04.032

DO - 10.1016/j.jcms.2016.04.032

M3 - Article

C2 - 27235151

AN - SCOPUS:84971619628

VL - 44

SP - 890

EP - 894

JO - Journal of Cranio-Maxillofacial Surgery

JF - Journal of Cranio-Maxillofacial Surgery

SN - 1010-5182

IS - 7

ER -