Incidence of apnea attack as allergic reaction after oral food challenge in patient with IgE-mediated wheat allergy

Masayuki Akashi

Research output: Contribution to journalArticlepeer-review

Abstract

Anaphylaxis is a severe allergic reaction that is rapid in onset and might cause death. Although wheezes, dyspnea or loss of consciousness are known to occur with severe allergic reactions with IgE-mediated food allergy, reports of apnea attack associated with IgE-mediated food allergy are rare. In this case, 9-year-old boy with IgE-mediated wheat allergy experienced apnea attack with strong desaturation after an immediate allergic reaction including erythema, abdominal pain, vomiting, and anaphylactic shock. The patient had asphyxia and cyanosis confirmed by medical staff when his oxygen saturation decreased to the 60% level, and he had occasional asphyxia over 10 seconds with no thoracic motion after a desaturation episode. Central apnea attack might be occurred in patient with IgE-mediated food allergy. However, the exact mechanism responsible remains unknown and further research is needed.

Original languageEnglish
Pages (from-to)1018-1021
Number of pages4
JournalJapanese Journal of Allergology
Volume65
Issue number8
Publication statusPublished - 2016
Externally publishedYes

Keywords

  • Apnea attack
  • IgE-mediated wheat allergy
  • Oral food challenge test

ASJC Scopus subject areas

  • Immunology and Allergy

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