Increase in blood flow and shear stress to nonworking limbs during incremental exercise

Hirofumi Tanaka, Shizuyo Shimizu-Okuyama, Fumiko Ohmori, Yoshiho Muraoka, Mana Kumagai, Mutsuko Yoshizawa, Atsuko Kagaya

Research output: Contribution to journalArticle

72 Citations (Scopus)

Abstract

Purpose: Regular exercise augments endothelium-dependent vasodilatory capacity in the vasculature located in the nonworking limbs. We determined whether blood flow as well as shear stress would change in inactive limbs during acute incremental exercise. Methods: Eight young healthy female subjects performed graded exercise on arm and leg cycle ergometers that had been modified to minimize the movement of nonworking limbs and to facilitate the placement of Doppler transducers. Both brachial and femoral blood flow was monitored using Doppler ultrasonography. EMG activity was also measured to document that there was no muscular activity in nonworking muscles. Results: During leg exercise, brachial blood flow and calculated shear stress gradually and curvilinearly increased (P < 0.05). At the peak work rate, there was an approximately fourfold increase in blood flow in the brachial artery (19 ± 6 vs 77 ± 16 mL·min-1). Femoral blood flow and calculated shear stress increased progressively and linearly during arm exercise (P < 0.05). Conclusion: We concluded that blood flow to the nonworking limbs increases markedly in proportion to the work intensity. These results suggest that the conduit arteries in the nonworking limbs are exposed to increases in blood flow and shear stress during exercise.

Original languageEnglish
Pages (from-to)81-85
Number of pages5
JournalMedicine and Science in Sports and Exercise
Volume38
Issue number1
DOIs
Publication statusPublished - 2006 Jan
Externally publishedYes

Fingerprint

Extremities
Exercise
Arm
Thigh
Leg
Doppler Ultrasonography
Brachial Artery
Transducers
Endothelium
Healthy Volunteers
Arteries
Muscles

Keywords

  • Doppler ultrasonography
  • Endothelium
  • Hemodynamics
  • Inactive Muscle
  • Vasodilation

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Physical Therapy, Sports Therapy and Rehabilitation
  • Orthopedics and Sports Medicine

Cite this

Increase in blood flow and shear stress to nonworking limbs during incremental exercise. / Tanaka, Hirofumi; Shimizu-Okuyama, Shizuyo; Ohmori, Fumiko; Muraoka, Yoshiho; Kumagai, Mana; Yoshizawa, Mutsuko; Kagaya, Atsuko.

In: Medicine and Science in Sports and Exercise, Vol. 38, No. 1, 01.2006, p. 81-85.

Research output: Contribution to journalArticle

Tanaka, Hirofumi ; Shimizu-Okuyama, Shizuyo ; Ohmori, Fumiko ; Muraoka, Yoshiho ; Kumagai, Mana ; Yoshizawa, Mutsuko ; Kagaya, Atsuko. / Increase in blood flow and shear stress to nonworking limbs during incremental exercise. In: Medicine and Science in Sports and Exercise. 2006 ; Vol. 38, No. 1. pp. 81-85.
@article{aad26a59d1be42bb80029c6bee463fdc,
title = "Increase in blood flow and shear stress to nonworking limbs during incremental exercise",
abstract = "Purpose: Regular exercise augments endothelium-dependent vasodilatory capacity in the vasculature located in the nonworking limbs. We determined whether blood flow as well as shear stress would change in inactive limbs during acute incremental exercise. Methods: Eight young healthy female subjects performed graded exercise on arm and leg cycle ergometers that had been modified to minimize the movement of nonworking limbs and to facilitate the placement of Doppler transducers. Both brachial and femoral blood flow was monitored using Doppler ultrasonography. EMG activity was also measured to document that there was no muscular activity in nonworking muscles. Results: During leg exercise, brachial blood flow and calculated shear stress gradually and curvilinearly increased (P < 0.05). At the peak work rate, there was an approximately fourfold increase in blood flow in the brachial artery (19 ± 6 vs 77 ± 16 mL·min-1). Femoral blood flow and calculated shear stress increased progressively and linearly during arm exercise (P < 0.05). Conclusion: We concluded that blood flow to the nonworking limbs increases markedly in proportion to the work intensity. These results suggest that the conduit arteries in the nonworking limbs are exposed to increases in blood flow and shear stress during exercise.",
keywords = "Doppler ultrasonography, Endothelium, Hemodynamics, Inactive Muscle, Vasodilation",
author = "Hirofumi Tanaka and Shizuyo Shimizu-Okuyama and Fumiko Ohmori and Yoshiho Muraoka and Mana Kumagai and Mutsuko Yoshizawa and Atsuko Kagaya",
year = "2006",
month = "1",
doi = "10.1249/01.mss.0000191166.81789.de",
language = "English",
volume = "38",
pages = "81--85",
journal = "Medicine and Science in Sports and Exercise",
issn = "0195-9131",
publisher = "Lippincott Williams and Wilkins",
number = "1",

}

TY - JOUR

T1 - Increase in blood flow and shear stress to nonworking limbs during incremental exercise

AU - Tanaka, Hirofumi

AU - Shimizu-Okuyama, Shizuyo

AU - Ohmori, Fumiko

AU - Muraoka, Yoshiho

AU - Kumagai, Mana

AU - Yoshizawa, Mutsuko

AU - Kagaya, Atsuko

PY - 2006/1

Y1 - 2006/1

N2 - Purpose: Regular exercise augments endothelium-dependent vasodilatory capacity in the vasculature located in the nonworking limbs. We determined whether blood flow as well as shear stress would change in inactive limbs during acute incremental exercise. Methods: Eight young healthy female subjects performed graded exercise on arm and leg cycle ergometers that had been modified to minimize the movement of nonworking limbs and to facilitate the placement of Doppler transducers. Both brachial and femoral blood flow was monitored using Doppler ultrasonography. EMG activity was also measured to document that there was no muscular activity in nonworking muscles. Results: During leg exercise, brachial blood flow and calculated shear stress gradually and curvilinearly increased (P < 0.05). At the peak work rate, there was an approximately fourfold increase in blood flow in the brachial artery (19 ± 6 vs 77 ± 16 mL·min-1). Femoral blood flow and calculated shear stress increased progressively and linearly during arm exercise (P < 0.05). Conclusion: We concluded that blood flow to the nonworking limbs increases markedly in proportion to the work intensity. These results suggest that the conduit arteries in the nonworking limbs are exposed to increases in blood flow and shear stress during exercise.

AB - Purpose: Regular exercise augments endothelium-dependent vasodilatory capacity in the vasculature located in the nonworking limbs. We determined whether blood flow as well as shear stress would change in inactive limbs during acute incremental exercise. Methods: Eight young healthy female subjects performed graded exercise on arm and leg cycle ergometers that had been modified to minimize the movement of nonworking limbs and to facilitate the placement of Doppler transducers. Both brachial and femoral blood flow was monitored using Doppler ultrasonography. EMG activity was also measured to document that there was no muscular activity in nonworking muscles. Results: During leg exercise, brachial blood flow and calculated shear stress gradually and curvilinearly increased (P < 0.05). At the peak work rate, there was an approximately fourfold increase in blood flow in the brachial artery (19 ± 6 vs 77 ± 16 mL·min-1). Femoral blood flow and calculated shear stress increased progressively and linearly during arm exercise (P < 0.05). Conclusion: We concluded that blood flow to the nonworking limbs increases markedly in proportion to the work intensity. These results suggest that the conduit arteries in the nonworking limbs are exposed to increases in blood flow and shear stress during exercise.

KW - Doppler ultrasonography

KW - Endothelium

KW - Hemodynamics

KW - Inactive Muscle

KW - Vasodilation

UR - http://www.scopus.com/inward/record.url?scp=30344466952&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=30344466952&partnerID=8YFLogxK

U2 - 10.1249/01.mss.0000191166.81789.de

DO - 10.1249/01.mss.0000191166.81789.de

M3 - Article

C2 - 16394957

AN - SCOPUS:30344466952

VL - 38

SP - 81

EP - 85

JO - Medicine and Science in Sports and Exercise

JF - Medicine and Science in Sports and Exercise

SN - 0195-9131

IS - 1

ER -