Increased DNA-incorporated thiopurine metabolite as a possible mechanism for leukocytopenia through cell apoptosis in inflammatory bowel disease patients with NUDT15 mutation

Takahiko Toyonaga, Taku Kobayashi, Satoshi Kuronuma, Aito Ueno, Hiroki Kiyohara, Shinji Okabayashi, Osamu Takeuchi, Christopher P.F. Redfern, Hideki Terai, Ryo Ozaki, Shintaro Sagami, Masaru Nakano, Sally A. Coulthard, Yoichi Tanaka, Toshifumi Hibi

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Medicine & Life Sciences