Induction of chromosome damage by benzo[a]pyrene, 2-aminofluorene and cyclophosphamide in the root cells of Vicia faba

Nobuhiro Kanaya

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The induction of sister-chromatid exchanges (SCEs) and chromosome aberrations (CAs) by benzo[a]pyrene (BP), 2-aminofluorene (2-AF) and cyclophosphamide (CP) in the root cells of Vicia faba was examined. BP and 2-AF induced CAs, but not SCEs. CP induced both SCEs and CAs.

Original languageEnglish
Pages (from-to)187-192
Number of pages6
JournalMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
Volume228
Issue number2
DOIs
Publication statusPublished - 1990

Fingerprint

Vicia faba
Sister Chromatid Exchange
Benzo(a)pyrene
Chromosome Aberrations
Cyclophosphamide
Chromosomes
2-aminofluorene

Keywords

  • 2-Aminofluorene
  • Benzo[a]pyrene
  • Chromosome aberration
  • Cyclophosphamide
  • Sister-chromatid exchanges
  • Vicia faba

ASJC Scopus subject areas

  • Molecular Biology
  • Health, Toxicology and Mutagenesis
  • Medicine(all)

Cite this

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abstract = "The induction of sister-chromatid exchanges (SCEs) and chromosome aberrations (CAs) by benzo[a]pyrene (BP), 2-aminofluorene (2-AF) and cyclophosphamide (CP) in the root cells of Vicia faba was examined. BP and 2-AF induced CAs, but not SCEs. CP induced both SCEs and CAs.",
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AB - The induction of sister-chromatid exchanges (SCEs) and chromosome aberrations (CAs) by benzo[a]pyrene (BP), 2-aminofluorene (2-AF) and cyclophosphamide (CP) in the root cells of Vicia faba was examined. BP and 2-AF induced CAs, but not SCEs. CP induced both SCEs and CAs.

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KW - Cyclophosphamide

KW - Sister-chromatid exchanges

KW - Vicia faba

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