Various fluoroquinolones (norfloxacin, enoxacin, ofloxacin, levofloxacin, and sparfloxacin) induce DnaK and GroEL heat shock proteins in Escherichia coli. The induction is transient, consistent with the kinetics of cellular DNA relaxation. The concentrations of fluoroquinolones required for the induction are similar to those required for DNA relaxation and much higher than those required for cell death.
|Number of pages||3|
|Journal||Antimicrobial Agents and Chemotherapy|
|Publication status||Published - 1997 Jan 7|
ASJC Scopus subject areas
- Pharmacology (medical)
- Infectious Diseases