[Infantile meningitis caused by respiratory syncytial virus].

G. Shirota, Miyuki Morozumi, Kimiko Ubukata, Hiroyuki Shiro

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Respiratory syncytial (RS) virus commonly causes infantile respiratory tract infection causing significant morbidity and mortality, but rarely meningitis. We report a case of meningitis caused by RS virus subgroup B in a 56-day-old boy admitted for high fever who underwent blood examination and lumbar puncture. Empirical chemotherapy was started with intravenous ampicillin, gentamicin, and cefotaxime based on laboratory data on CSF cells (84/microL) and serum CRP (13.8mg/dL) data. RS virus subgroup B was only detected using real-time PCR comprehensive reverse transcription from the first CSF, but no bacterial gene was detected. No bacteria grew from his CSF, urine, or blood. Fever and serum CRP dropped in a few days. He had neither seizures nor disturbance of consciousness and was discharged on day 11 after admission. No evidence of encephalopathy was detected in brain MRI or electroencephalography. RS virus rarely causes meningitis, but a percentage of RS-virus-infected infants exhibit symptoms such as seizure and disturbance of consciousness. We should recognize that the RS virus may cause neurological complications associated with high morbidity and mortality.

Original languageEnglish
Pages (from-to)682-685
Number of pages4
JournalKansenshōgaku zasshi. The Journal of the Japanese Association for Infectious Diseases
Volume85
Issue number6
DOIs
Publication statusPublished - 2011 Nov

ASJC Scopus subject areas

  • Medicine(all)

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