[Inflammatory bowel disease and colorectal cancer].

Tadakazu Hisamatsu

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Inflammatory bowel disease (IBD), ulcerative colitis (UC) and Crohn's disease (CD), have been considered as a risk of colorectal cancer (CRC). CRC associated with chronic intestinal inflammation has been known as "colitic cancer". Molecular mechanisms for developing of colitic cancer are different from those of sporadic CRC known as adenomacarcinoma sequence. Colitic cancer often involves dysplasia as precancerous lesions. Mutation of p53 gene is often observed not only in colitic cancer but also in dysplasia. Theory of "field cancerization" applies in colitic cancer resulting in several difficulties in clinical management of it such as multifocality and heterochrony.

Original languageEnglish
Pages (from-to)56-62
Number of pages7
JournalUnknown Journal
Volume72
Issue number1
Publication statusPublished - 2014

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Colorectal Cancer
Inflammatory Bowel Diseases
Colorectal Neoplasms
Cancer
cancer
Disease
Neoplasms
Inflammation
p53 Genes
Ulcerative Colitis
Crohn Disease
Mutation
Colorectal cancer
Gene

ASJC Scopus subject areas

  • Medicine(all)

Cite this

[Inflammatory bowel disease and colorectal cancer]. / Hisamatsu, Tadakazu.

In: Unknown Journal, Vol. 72, No. 1, 2014, p. 56-62.

Research output: Contribution to journalArticle

Hisamatsu, T 2014, '[Inflammatory bowel disease and colorectal cancer].', Unknown Journal, vol. 72, no. 1, pp. 56-62.
Hisamatsu, Tadakazu. / [Inflammatory bowel disease and colorectal cancer]. In: Unknown Journal. 2014 ; Vol. 72, No. 1. pp. 56-62.
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