Inflammatory plaque with peripheral nodules

A new specific finding of cutaneous polyarteritis nodosa

Po Tak Chan, Akira Ishiko, Naoko Wada, Nao Yamamoto, Masayuki Amagai

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Cutaneous polyarteritis nodosa commonly affects the distal lower limbs, presenting as nodules, ulcers, and livedo reticularis. We report five cases to illustrate a new specific presentation of cutaneous polyarteritis nodosa on the trunk or proximal extremities. In the acute stage, lesions were tender erythematous plaques. On palpation, 1- to 2-cm diameter subcutaneous nodules were found along the periphery. The lesions responded to dapsone, aspirin, nonsteroidal antiinflammatory drugs, or systemic steroids and healed with postinflammatory hyperpigmentation. Systemic polyarteritis nodosa did not develop in any patient after a follow-up time ranging from 9 months to 9 years. The presence of small nodules at the periphery of an inflammatory plaque was a useful clinical clue, because this prompted us to suspect cutaneous polyarteritis nodosa when we encountered similar cases later, which could be confirmed histologically. In conclusion, cutaneous polyarteritis nodosa can present as inflammatory plaques on the trunk and proximal extremities, and the presence of peripheral nodules around these plaques constitutes a useful clinical clue to its diagnosis.

Original languageEnglish
Pages (from-to)320-325
Number of pages6
JournalJournal of the American Academy of Dermatology
Volume60
Issue number2
DOIs
Publication statusPublished - 2009 Feb

Fingerprint

Polyarteritis Nodosa
Skin
Extremities
Livedo Reticularis
Dapsone
Hyperpigmentation
Palpation
Aspirin
Ulcer
Lower Extremity
Anti-Inflammatory Agents
Steroids
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Dermatology

Cite this

Inflammatory plaque with peripheral nodules : A new specific finding of cutaneous polyarteritis nodosa. / Chan, Po Tak; Ishiko, Akira; Wada, Naoko; Yamamoto, Nao; Amagai, Masayuki.

In: Journal of the American Academy of Dermatology, Vol. 60, No. 2, 02.2009, p. 320-325.

Research output: Contribution to journalArticle

@article{030799a9f442431daf3ec400c0365778,
title = "Inflammatory plaque with peripheral nodules: A new specific finding of cutaneous polyarteritis nodosa",
abstract = "Cutaneous polyarteritis nodosa commonly affects the distal lower limbs, presenting as nodules, ulcers, and livedo reticularis. We report five cases to illustrate a new specific presentation of cutaneous polyarteritis nodosa on the trunk or proximal extremities. In the acute stage, lesions were tender erythematous plaques. On palpation, 1- to 2-cm diameter subcutaneous nodules were found along the periphery. The lesions responded to dapsone, aspirin, nonsteroidal antiinflammatory drugs, or systemic steroids and healed with postinflammatory hyperpigmentation. Systemic polyarteritis nodosa did not develop in any patient after a follow-up time ranging from 9 months to 9 years. The presence of small nodules at the periphery of an inflammatory plaque was a useful clinical clue, because this prompted us to suspect cutaneous polyarteritis nodosa when we encountered similar cases later, which could be confirmed histologically. In conclusion, cutaneous polyarteritis nodosa can present as inflammatory plaques on the trunk and proximal extremities, and the presence of peripheral nodules around these plaques constitutes a useful clinical clue to its diagnosis.",
author = "Chan, {Po Tak} and Akira Ishiko and Naoko Wada and Nao Yamamoto and Masayuki Amagai",
year = "2009",
month = "2",
doi = "10.1016/j.jaad.2008.08.042",
language = "English",
volume = "60",
pages = "320--325",
journal = "Journal of the American Academy of Dermatology",
issn = "0190-9622",
publisher = "Mosby Inc.",
number = "2",

}

TY - JOUR

T1 - Inflammatory plaque with peripheral nodules

T2 - A new specific finding of cutaneous polyarteritis nodosa

AU - Chan, Po Tak

AU - Ishiko, Akira

AU - Wada, Naoko

AU - Yamamoto, Nao

AU - Amagai, Masayuki

PY - 2009/2

Y1 - 2009/2

N2 - Cutaneous polyarteritis nodosa commonly affects the distal lower limbs, presenting as nodules, ulcers, and livedo reticularis. We report five cases to illustrate a new specific presentation of cutaneous polyarteritis nodosa on the trunk or proximal extremities. In the acute stage, lesions were tender erythematous plaques. On palpation, 1- to 2-cm diameter subcutaneous nodules were found along the periphery. The lesions responded to dapsone, aspirin, nonsteroidal antiinflammatory drugs, or systemic steroids and healed with postinflammatory hyperpigmentation. Systemic polyarteritis nodosa did not develop in any patient after a follow-up time ranging from 9 months to 9 years. The presence of small nodules at the periphery of an inflammatory plaque was a useful clinical clue, because this prompted us to suspect cutaneous polyarteritis nodosa when we encountered similar cases later, which could be confirmed histologically. In conclusion, cutaneous polyarteritis nodosa can present as inflammatory plaques on the trunk and proximal extremities, and the presence of peripheral nodules around these plaques constitutes a useful clinical clue to its diagnosis.

AB - Cutaneous polyarteritis nodosa commonly affects the distal lower limbs, presenting as nodules, ulcers, and livedo reticularis. We report five cases to illustrate a new specific presentation of cutaneous polyarteritis nodosa on the trunk or proximal extremities. In the acute stage, lesions were tender erythematous plaques. On palpation, 1- to 2-cm diameter subcutaneous nodules were found along the periphery. The lesions responded to dapsone, aspirin, nonsteroidal antiinflammatory drugs, or systemic steroids and healed with postinflammatory hyperpigmentation. Systemic polyarteritis nodosa did not develop in any patient after a follow-up time ranging from 9 months to 9 years. The presence of small nodules at the periphery of an inflammatory plaque was a useful clinical clue, because this prompted us to suspect cutaneous polyarteritis nodosa when we encountered similar cases later, which could be confirmed histologically. In conclusion, cutaneous polyarteritis nodosa can present as inflammatory plaques on the trunk and proximal extremities, and the presence of peripheral nodules around these plaques constitutes a useful clinical clue to its diagnosis.

UR - http://www.scopus.com/inward/record.url?scp=58149345022&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=58149345022&partnerID=8YFLogxK

U2 - 10.1016/j.jaad.2008.08.042

DO - 10.1016/j.jaad.2008.08.042

M3 - Article

VL - 60

SP - 320

EP - 325

JO - Journal of the American Academy of Dermatology

JF - Journal of the American Academy of Dermatology

SN - 0190-9622

IS - 2

ER -