Abstract
Background: Ageing is known to augment perioperative cardiac risk in non-cardiac surgery. However, it remains unclear whether the increased risk is attributable to ageing itself or to the associated cardiac risk factors and coronary artery disease. Methods: This retrospective study enrolled 1,351 patients who underwent non-cardiac surgery after dipyridamole stress myocardial perfusion scintigraphy. These patients were divided into the following four groups: Group 1-E (aged 75 or more, normal single photon emission computed tomography (SPECT)), Group 1-Y (aged less than 75, normal SPECT), Group 2-E (aged 75 or more, abnormal SPECT) and Group 2-Y (aged less than 75, abnormal SPECT). Clinical risk factors, scintigraphic findings and occurrence of perioperative cardiac events were analysed. Results: The older cohorts had a significantly higher number of risk factors than their younger counterparts. No significant difference was observed in the degree of perfusion abnormality between Groups 2-E and 2-Y. Although the event rates were comparable in Groups 1-E and 1-Y, Group 2-E yielded a significantly higher rate than Group 2-Y. Ageing was an independent predictor of cardiac events in Group 2 in multivariate analysis. Conclusions: Ageing has no influence on perioperative cardiac risk in patients without overt myocardial infarction or ischaemia. The likelihood of cardiac events is increased by ageing, independently of other variables, in patients with perfusion abnormality.
| Original language | English |
|---|---|
| Pages (from-to) | 68-72 |
| Number of pages | 5 |
| Journal | Age and Ageing |
| Volume | 36 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 2007 Jan |
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Keywords
- Ageing
- Dipyridamole stress
- Elderly
- Myocardial perfusion scintigraphy
- Perioperative cardiac event
- SPECT
ASJC Scopus subject areas
- Ageing
Cite this
Influence of ageing on perioperative cardiac risk in non-cardiac surgery. / Bai, Jingming; Hashimoto, Jun; Nakahara, Tadaki; Suzuki, Takayuki; Kubo, Atsushi.
In: Age and Ageing, Vol. 36, No. 1, 01.2007, p. 68-72.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Influence of ageing on perioperative cardiac risk in non-cardiac surgery
AU - Bai, Jingming
AU - Hashimoto, Jun
AU - Nakahara, Tadaki
AU - Suzuki, Takayuki
AU - Kubo, Atsushi
PY - 2007/1
Y1 - 2007/1
N2 - Background: Ageing is known to augment perioperative cardiac risk in non-cardiac surgery. However, it remains unclear whether the increased risk is attributable to ageing itself or to the associated cardiac risk factors and coronary artery disease. Methods: This retrospective study enrolled 1,351 patients who underwent non-cardiac surgery after dipyridamole stress myocardial perfusion scintigraphy. These patients were divided into the following four groups: Group 1-E (aged 75 or more, normal single photon emission computed tomography (SPECT)), Group 1-Y (aged less than 75, normal SPECT), Group 2-E (aged 75 or more, abnormal SPECT) and Group 2-Y (aged less than 75, abnormal SPECT). Clinical risk factors, scintigraphic findings and occurrence of perioperative cardiac events were analysed. Results: The older cohorts had a significantly higher number of risk factors than their younger counterparts. No significant difference was observed in the degree of perfusion abnormality between Groups 2-E and 2-Y. Although the event rates were comparable in Groups 1-E and 1-Y, Group 2-E yielded a significantly higher rate than Group 2-Y. Ageing was an independent predictor of cardiac events in Group 2 in multivariate analysis. Conclusions: Ageing has no influence on perioperative cardiac risk in patients without overt myocardial infarction or ischaemia. The likelihood of cardiac events is increased by ageing, independently of other variables, in patients with perfusion abnormality.
AB - Background: Ageing is known to augment perioperative cardiac risk in non-cardiac surgery. However, it remains unclear whether the increased risk is attributable to ageing itself or to the associated cardiac risk factors and coronary artery disease. Methods: This retrospective study enrolled 1,351 patients who underwent non-cardiac surgery after dipyridamole stress myocardial perfusion scintigraphy. These patients were divided into the following four groups: Group 1-E (aged 75 or more, normal single photon emission computed tomography (SPECT)), Group 1-Y (aged less than 75, normal SPECT), Group 2-E (aged 75 or more, abnormal SPECT) and Group 2-Y (aged less than 75, abnormal SPECT). Clinical risk factors, scintigraphic findings and occurrence of perioperative cardiac events were analysed. Results: The older cohorts had a significantly higher number of risk factors than their younger counterparts. No significant difference was observed in the degree of perfusion abnormality between Groups 2-E and 2-Y. Although the event rates were comparable in Groups 1-E and 1-Y, Group 2-E yielded a significantly higher rate than Group 2-Y. Ageing was an independent predictor of cardiac events in Group 2 in multivariate analysis. Conclusions: Ageing has no influence on perioperative cardiac risk in patients without overt myocardial infarction or ischaemia. The likelihood of cardiac events is increased by ageing, independently of other variables, in patients with perfusion abnormality.
KW - Ageing
KW - Dipyridamole stress
KW - Elderly
KW - Myocardial perfusion scintigraphy
KW - Perioperative cardiac event
KW - SPECT
UR - http://www.scopus.com/inward/record.url?scp=33947581111&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33947581111&partnerID=8YFLogxK
U2 - 10.1093/ageing/afl130
DO - 10.1093/ageing/afl130
M3 - Article
C2 - 17175563
AN - SCOPUS:33947581111
VL - 36
SP - 68
EP - 72
JO - Age and Ageing
JF - Age and Ageing
SN - 0002-0729
IS - 1
ER -