Influence of anisotropic bone properties on the biomechanical behavior of the acetabular cup implant

a multiscale finite element study

Vu Hieu Nguyen, Giuseppe Rosi, Salah Naili, Adrien Michel, Maria Letizia Raffa, Romain Bosc, Jean Paul Meningaud, Christine Chappard, Naoki Takano, Guillaume Haiat

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Although the biomechanical behavior of the acetabular cup (AC) implant is determinant for the surgical success, it remains difficult to be assessed due to the multiscale and anisotropic nature of bone tissue. The aim of the present study was to investigate the influence of the anisotropic properties of peri-implant trabecular bone tissue on the biomechanical behavior of the AC implant at the macroscopic scale. Thirteen bovine trabecular bone samples were imaged using micro-computed tomography (μCT) with a resolution of 18 μm. The anisotropic biomechanical properties of each sample were determined at the scale of the centimeter based on a dedicated method using asymptotic homogenization. The material properties obtained with this multiscale approach were used as input data in a 3D finite element model to simulate the macroscopic mechanical behavior of the AC implant under different loading conditions. The largest stress and strain magnitudes were found around the equatorial rim and in the polar area of the AC implant. All macroscopic stiffness quantities were significantly correlated (R2 > 0.85, p < 6.5 e-6) with BV/TV (bone volume/total volume). Moreover, the maximum value of the von Mises stress field was significantly correlated with BV/TV (R2 > 0.61, p < 1.6 e-3) and was always found at the bone-implant interface. However, the mean value of the microscopic stress (at the scale of the trabeculae) decrease as a function of BV/TV for vertical and torsional loading and do not depend on BV/TV for horizontal loading. These results highlight the importance of the anisotropic properties of bone tissue.

Original languageEnglish
Pages (from-to)1-14
Number of pages14
JournalComputer Methods in Biomechanics and Biomedical Engineering
DOIs
Publication statusAccepted/In press - 2017 Aug 3

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Bone
Tissue
Tomography
Materials properties
Stiffness

Keywords

  • Acetabular cup
  • bone
  • finite element analysis
  • homogenization
  • total hip replacement

ASJC Scopus subject areas

  • Bioengineering
  • Biomedical Engineering
  • Human-Computer Interaction
  • Computer Science Applications

Cite this

Influence of anisotropic bone properties on the biomechanical behavior of the acetabular cup implant : a multiscale finite element study. / Nguyen, Vu Hieu; Rosi, Giuseppe; Naili, Salah; Michel, Adrien; Raffa, Maria Letizia; Bosc, Romain; Meningaud, Jean Paul; Chappard, Christine; Takano, Naoki; Haiat, Guillaume.

In: Computer Methods in Biomechanics and Biomedical Engineering, 03.08.2017, p. 1-14.

Research output: Contribution to journalArticle

Nguyen, Vu Hieu ; Rosi, Giuseppe ; Naili, Salah ; Michel, Adrien ; Raffa, Maria Letizia ; Bosc, Romain ; Meningaud, Jean Paul ; Chappard, Christine ; Takano, Naoki ; Haiat, Guillaume. / Influence of anisotropic bone properties on the biomechanical behavior of the acetabular cup implant : a multiscale finite element study. In: Computer Methods in Biomechanics and Biomedical Engineering. 2017 ; pp. 1-14.
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