TY - JOUR
T1 - Influence of anisotropic bone properties on the biomechanical behavior of the acetabular cup implant
T2 - a multiscale finite element study
AU - Nguyen, Vu Hieu
AU - Rosi, Giuseppe
AU - Naili, Salah
AU - Michel, Adrien
AU - Raffa, Maria Letizia
AU - Bosc, Romain
AU - Meningaud, Jean Paul
AU - Chappard, Christine
AU - Takano, Naoki
AU - Haiat, Guillaume
N1 - Funding Information:
This work has been supported by French National Research Agency (ANR) through the PRTS program [project OsseoWave n°ANR-13-PRTS-0015-02]; Ecole Doctorale SIE of the UPE for the funding of AM in Keio University; European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program [grant agreement number 682001, project ERC Consolidator Grant 2015 BoneImplant]. The authors acknowledge the support of the Ecole Doctorale SIE of the UPE for the funding of AM in Keio University and the help of Mr. Kyohei Hatano to run the computations.
Publisher Copyright:
© 2017 Informa UK Limited, trading as Taylor & Francis Group.
PY - 2017/9/10
Y1 - 2017/9/10
N2 - Although the biomechanical behavior of the acetabular cup (AC) implant is determinant for the surgical success, it remains difficult to be assessed due to the multiscale and anisotropic nature of bone tissue. The aim of the present study was to investigate the influence of the anisotropic properties of peri-implant trabecular bone tissue on the biomechanical behavior of the AC implant at the macroscopic scale. Thirteen bovine trabecular bone samples were imaged using micro-computed tomography (μCT) with a resolution of 18 μm. The anisotropic biomechanical properties of each sample were determined at the scale of the centimeter based on a dedicated method using asymptotic homogenization. The material properties obtained with this multiscale approach were used as input data in a 3D finite element model to simulate the macroscopic mechanical behavior of the AC implant under different loading conditions. The largest stress and strain magnitudes were found around the equatorial rim and in the polar area of the AC implant. All macroscopic stiffness quantities were significantly correlated (R2 > 0.85, p < 6.5 e-6) with BV/TV (bone volume/total volume). Moreover, the maximum value of the von Mises stress field was significantly correlated with BV/TV (R2 > 0.61, p < 1.6 e-3) and was always found at the bone-implant interface. However, the mean value of the microscopic stress (at the scale of the trabeculae) decrease as a function of BV/TV for vertical and torsional loading and do not depend on BV/TV for horizontal loading. These results highlight the importance of the anisotropic properties of bone tissue.
AB - Although the biomechanical behavior of the acetabular cup (AC) implant is determinant for the surgical success, it remains difficult to be assessed due to the multiscale and anisotropic nature of bone tissue. The aim of the present study was to investigate the influence of the anisotropic properties of peri-implant trabecular bone tissue on the biomechanical behavior of the AC implant at the macroscopic scale. Thirteen bovine trabecular bone samples were imaged using micro-computed tomography (μCT) with a resolution of 18 μm. The anisotropic biomechanical properties of each sample were determined at the scale of the centimeter based on a dedicated method using asymptotic homogenization. The material properties obtained with this multiscale approach were used as input data in a 3D finite element model to simulate the macroscopic mechanical behavior of the AC implant under different loading conditions. The largest stress and strain magnitudes were found around the equatorial rim and in the polar area of the AC implant. All macroscopic stiffness quantities were significantly correlated (R2 > 0.85, p < 6.5 e-6) with BV/TV (bone volume/total volume). Moreover, the maximum value of the von Mises stress field was significantly correlated with BV/TV (R2 > 0.61, p < 1.6 e-3) and was always found at the bone-implant interface. However, the mean value of the microscopic stress (at the scale of the trabeculae) decrease as a function of BV/TV for vertical and torsional loading and do not depend on BV/TV for horizontal loading. These results highlight the importance of the anisotropic properties of bone tissue.
KW - Acetabular cup
KW - bone
KW - finite element analysis
KW - homogenization
KW - total hip replacement
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U2 - 10.1080/10255842.2017.1357703
DO - 10.1080/10255842.2017.1357703
M3 - Article
C2 - 28768422
AN - SCOPUS:85026884591
SN - 1025-5842
VL - 20
SP - 1312
EP - 1325
JO - Computer Methods in Biomechanics and Biomedical Engineering
JF - Computer Methods in Biomechanics and Biomedical Engineering
IS - 12
ER -