Influence of lack of posterior occlusal support on cognitive decline among 80-year-old Japanese people in a 3-year prospective study

Kodai Hatta, Kazunori Ikebe, Yasuyuki Gondo, Kei Kamide, Yukie Masui, Hiroki Inagaki, Takeshi Nakagawa, Ken ichi Matsuda, Taiji Ogawa, Chisato Inomata, Hajime Takeshita, Yusuke Mihara, Motoyoshi Fukutake, Masahiro Kitamura, Shinya Murakami, Mai Kabayama, Tatsuro Ishizaki, Yasumichi Arai, Ken Sugimoto, Hiromi RakugiYoshinobu Maeda

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Aim: Previous studies have reported significant associations between tooth loss or periodontal status and cognitive function; however, animal experimental studies have shown that occlusion might be a more important factor in cognitive decline. The purpose of the present study was to investigate the influence of a lack of posterior occlusal support by residual teeth on the decline of cognitive function over a 3-year period among 80-year-old Japanese people. Methods: Participants were community-dwelling older adults (n = 515, age 79–81 years). Cognitive function was measured using the Japanese version of the Montreal Cognitive Assessment. At baseline, participants were divided into two groups: those with and without posterior occlusal support. Participants whose Japanese version of the Montreal Cognitive Assessment score decreased by ≥3 points over the 3-year period were defined as the declined group. Logistic regression was carried out for the decline in Japanese version of the Montreal Cognitive Assessment scores, including dental status and possible risk factors as independent variables. Results: More participants without posterior occlusal support tended to be in the cognitive decline group (49.4%) than in the maintained group (38.5%; χ2-test, P = 0.02). Logistic regression analysis showed that a lack of posterior occlusal support was a significant variable (odds ratio 1.55, P = 0.03) for cognitive decline, even after adjusting for other risk factors. However, the number of teeth or mean periodontal pocket depth was not significantly correlated with cognitive decline. Conclusions: The present findings suggest that a lack of posterior occlusal support predicted the incidence of cognitive decline, even after adjusting for possible risk factors in community-dwelling old-old people. Geriatr Gerontol Int 2018; 18: 1439–1446.

Original languageEnglish
Pages (from-to)1439-1446
Number of pages8
JournalGeriatrics and Gerontology International
Volume18
Issue number10
DOIs
Publication statusPublished - 2018 Oct 1

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Prospective Studies
lack
Cognition
Independent Living
Tooth
Group
logistics
Logistic Models
Periodontal Pocket
Tooth Loss
community
regression analysis
incidence
animal
regression
Odds Ratio
Regression Analysis
Cognitive Dysfunction
Incidence

Keywords

  • cognitive function
  • cohort study
  • community-dwelling older adults
  • oral status
  • risk factor

ASJC Scopus subject areas

  • Health(social science)
  • Gerontology
  • Geriatrics and Gerontology

Cite this

Influence of lack of posterior occlusal support on cognitive decline among 80-year-old Japanese people in a 3-year prospective study. / Hatta, Kodai; Ikebe, Kazunori; Gondo, Yasuyuki; Kamide, Kei; Masui, Yukie; Inagaki, Hiroki; Nakagawa, Takeshi; Matsuda, Ken ichi; Ogawa, Taiji; Inomata, Chisato; Takeshita, Hajime; Mihara, Yusuke; Fukutake, Motoyoshi; Kitamura, Masahiro; Murakami, Shinya; Kabayama, Mai; Ishizaki, Tatsuro; Arai, Yasumichi; Sugimoto, Ken; Rakugi, Hiromi; Maeda, Yoshinobu.

In: Geriatrics and Gerontology International, Vol. 18, No. 10, 01.10.2018, p. 1439-1446.

Research output: Contribution to journalArticle

Hatta, K, Ikebe, K, Gondo, Y, Kamide, K, Masui, Y, Inagaki, H, Nakagawa, T, Matsuda, KI, Ogawa, T, Inomata, C, Takeshita, H, Mihara, Y, Fukutake, M, Kitamura, M, Murakami, S, Kabayama, M, Ishizaki, T, Arai, Y, Sugimoto, K, Rakugi, H & Maeda, Y 2018, 'Influence of lack of posterior occlusal support on cognitive decline among 80-year-old Japanese people in a 3-year prospective study', Geriatrics and Gerontology International, vol. 18, no. 10, pp. 1439-1446. https://doi.org/10.1111/ggi.13508
Hatta, Kodai ; Ikebe, Kazunori ; Gondo, Yasuyuki ; Kamide, Kei ; Masui, Yukie ; Inagaki, Hiroki ; Nakagawa, Takeshi ; Matsuda, Ken ichi ; Ogawa, Taiji ; Inomata, Chisato ; Takeshita, Hajime ; Mihara, Yusuke ; Fukutake, Motoyoshi ; Kitamura, Masahiro ; Murakami, Shinya ; Kabayama, Mai ; Ishizaki, Tatsuro ; Arai, Yasumichi ; Sugimoto, Ken ; Rakugi, Hiromi ; Maeda, Yoshinobu. / Influence of lack of posterior occlusal support on cognitive decline among 80-year-old Japanese people in a 3-year prospective study. In: Geriatrics and Gerontology International. 2018 ; Vol. 18, No. 10. pp. 1439-1446.
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abstract = "Aim: Previous studies have reported significant associations between tooth loss or periodontal status and cognitive function; however, animal experimental studies have shown that occlusion might be a more important factor in cognitive decline. The purpose of the present study was to investigate the influence of a lack of posterior occlusal support by residual teeth on the decline of cognitive function over a 3-year period among 80-year-old Japanese people. Methods: Participants were community-dwelling older adults (n = 515, age 79–81 years). Cognitive function was measured using the Japanese version of the Montreal Cognitive Assessment. At baseline, participants were divided into two groups: those with and without posterior occlusal support. Participants whose Japanese version of the Montreal Cognitive Assessment score decreased by ≥3 points over the 3-year period were defined as the declined group. Logistic regression was carried out for the decline in Japanese version of the Montreal Cognitive Assessment scores, including dental status and possible risk factors as independent variables. Results: More participants without posterior occlusal support tended to be in the cognitive decline group (49.4{\%}) than in the maintained group (38.5{\%}; χ2-test, P = 0.02). Logistic regression analysis showed that a lack of posterior occlusal support was a significant variable (odds ratio 1.55, P = 0.03) for cognitive decline, even after adjusting for other risk factors. However, the number of teeth or mean periodontal pocket depth was not significantly correlated with cognitive decline. Conclusions: The present findings suggest that a lack of posterior occlusal support predicted the incidence of cognitive decline, even after adjusting for possible risk factors in community-dwelling old-old people. Geriatr Gerontol Int 2018; 18: 1439–1446.",
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AU - Hatta, Kodai

AU - Ikebe, Kazunori

AU - Gondo, Yasuyuki

AU - Kamide, Kei

AU - Masui, Yukie

AU - Inagaki, Hiroki

AU - Nakagawa, Takeshi

AU - Matsuda, Ken ichi

AU - Ogawa, Taiji

AU - Inomata, Chisato

AU - Takeshita, Hajime

AU - Mihara, Yusuke

AU - Fukutake, Motoyoshi

AU - Kitamura, Masahiro

AU - Murakami, Shinya

AU - Kabayama, Mai

AU - Ishizaki, Tatsuro

AU - Arai, Yasumichi

AU - Sugimoto, Ken

AU - Rakugi, Hiromi

AU - Maeda, Yoshinobu

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N2 - Aim: Previous studies have reported significant associations between tooth loss or periodontal status and cognitive function; however, animal experimental studies have shown that occlusion might be a more important factor in cognitive decline. The purpose of the present study was to investigate the influence of a lack of posterior occlusal support by residual teeth on the decline of cognitive function over a 3-year period among 80-year-old Japanese people. Methods: Participants were community-dwelling older adults (n = 515, age 79–81 years). Cognitive function was measured using the Japanese version of the Montreal Cognitive Assessment. At baseline, participants were divided into two groups: those with and without posterior occlusal support. Participants whose Japanese version of the Montreal Cognitive Assessment score decreased by ≥3 points over the 3-year period were defined as the declined group. Logistic regression was carried out for the decline in Japanese version of the Montreal Cognitive Assessment scores, including dental status and possible risk factors as independent variables. Results: More participants without posterior occlusal support tended to be in the cognitive decline group (49.4%) than in the maintained group (38.5%; χ2-test, P = 0.02). Logistic regression analysis showed that a lack of posterior occlusal support was a significant variable (odds ratio 1.55, P = 0.03) for cognitive decline, even after adjusting for other risk factors. However, the number of teeth or mean periodontal pocket depth was not significantly correlated with cognitive decline. Conclusions: The present findings suggest that a lack of posterior occlusal support predicted the incidence of cognitive decline, even after adjusting for possible risk factors in community-dwelling old-old people. Geriatr Gerontol Int 2018; 18: 1439–1446.

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