Influence of perfusion depth on laser Doppler flow measurements with large source-detector spacing

Yohei Watanabe, Eiji Okada

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Laser Doppler flowmetry with a large source-detector spacing has been applied to measure blood perfusion in the deeper regions of tissue. The influence of the depth of perfusion on the Doppler spectrum for the large source-detector spacing is likely to be different from that for the conventional laser Doppler instruments with small source-detector spacing. In this study, the light propagation in a tissue model with a blood perfusion layer is predicted by the Monte Carlo simulation to discuss the influence of the depth of perfusion, blood volume, and source-detector spacing on the spectrum of the Doppler signal detected with large source-detector spacing. The influence of the depth of perfusion on the Doppler spectrum for the large source-detector spacing is different from that for the conventional laser Doppler instruments with small source-detector spacing, although the influence of source-detector spacing and blood volume on the Doppler spectrum for large source-detector spacing is almost the same as that for the conventional laser Doppler instruments. The influence of the depth of the perfusion on the Doppler spectrum depends on the path length that the detected light travels at different depths.

Original languageEnglish
Pages (from-to)3198-3204
Number of pages7
JournalApplied Optics
Volume42
Issue number16
Publication statusPublished - 2003 Jun 1

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flow measurement
Flow measurement
Light sources
spacing
Detectors
Lasers
detectors
lasers
Blood
blood volume
blood
Tissue
Light propagation
travel
propagation

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

Cite this

Influence of perfusion depth on laser Doppler flow measurements with large source-detector spacing. / Watanabe, Yohei; Okada, Eiji.

In: Applied Optics, Vol. 42, No. 16, 01.06.2003, p. 3198-3204.

Research output: Contribution to journalArticle

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