Inhibition of both COX-1 and COX-2 and resulting decrease in the level of prostaglandins E2 is responsible for non-steroidal anti-inflammatory drug (NSAID)-dependent exacerbation of colitis

Ken Ichiro Tanaka, Shintaro Suemasu, Tomoaki Ishihara, Yuichi Tasaka, Yasuhiro Arai, Tohru Mizushima

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Medicine & Life Sciences