Inhibitors of prostaglandin biosynthesis from Alpinia officinarum

Fumiyuki Kiuchi, Masaaki Shibuya, Ushio Sankawa

Research output: Contribution to journalArticle

75 Citations (Scopus)

Abstract

Three new diarylheptanoids were isolated as inhibitors of prostaglandin biosynthesis from the methanol extract of Alpinia officinarum Hance. Their structures were elucidated to be 7-(4″-hydroxy-3″-methoxyphenyl)-l-phenyl-3,5-heptadione (I), 5-methoxy-7-(4″-hydroxy-3″-methoxyphenyl)-l-phenyl-3-heptanone (IV), and 5-hydroxy-7-(4″-hydroxyphenyl)-l-phenyl-3-heptanone (VI) by the interpretation of spectral data.

Original languageEnglish
Pages (from-to)2279-2282
Number of pages4
JournalChemical and Pharmaceutical Bulletin
Volume30
Issue number6
DOIs
Publication statusPublished - 1982 Jan 1
Externally publishedYes

Keywords

  • Alpinia officinarum
  • Alpinia oxyphilla
  • Zingiberaceae
  • biosynthesis
  • diarylheptanoid
  • inhibitor
  • prostaglandin

ASJC Scopus subject areas

  • Chemistry(all)
  • Drug Discovery

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