Inhibitors of prostaglandin biosynthesis from ginger

Fumiyuki Kiuchi, Masaaki Shibuya, Ushio Sankawa

Research output: Contribution to journalArticle

146 Citations (Scopus)

Abstract

In addition to [6]-gingerol four new constituents were isolated as potent inhibitors of prostaglandin (PG) biosynthesis from ginger, the roots of Zingiber officinale Roscoe. Their structures were identified as [6]- and [10]-dehydrogingerdione (I and II) and [6]- and [10]-gingerdione (III and IV) by the interpretation of spectral data.

Original languageEnglish
Pages (from-to)754-757
Number of pages4
JournalChemical and Pharmaceutical Bulletin
Volume30
Issue number2
DOIs
Publication statusPublished - 1982 Jan 1
Externally publishedYes

Keywords

  • Zingiber officinale
  • Zingiberaceae
  • biosynthesis
  • dehydrogingerdione
  • ginger
  • gingerdione
  • gingerol
  • inhibitor
  • prostaglandin

ASJC Scopus subject areas

  • Chemistry(all)
  • Drug Discovery

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