Inhibitory effect of anti-lipid IV antiserum binding activity of various synthetic oligosaccharides

N. Hada, M. Sugita, T. Takeda, T. Maki, Y. Ogihara

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The inhibitory effects of various synthetic oligosaccharides (1-8) on anti-lipid IV antiserum binding activity were examined by ELISA (enzyme linked immunosorbent assay). Compound 8, containing an epitope GlcA-4Meβ1-4Fuc of lipid IV, inhibited but precursers (1-5) of lipid IV did not inhibit the binding activity. In addition to the nonreducing end disaccharide derivative (6) having a methyl group at position 4 of glucuronic acid, its analogous compound (7) having no methyl groups was synthesized and their inhibition activities were compared. Moreover, the inhibitory effects of compounds (1-5) were examined using each antiserum.

Original languageEnglish
Pages (from-to)333-341
Number of pages9
JournalYakugaku Zasshi
Volume114
Issue number5
Publication statusPublished - 1994
Externally publishedYes

Fingerprint

Oligosaccharides
Immune Sera
Glucuronic Acid
Disaccharides
Epitopes
Enzyme-Linked Immunosorbent Assay
Lipid IV

Keywords

  • anti-lipid IV antiserum
  • Hyriopsis schlegelii
  • inhibitory effect
  • lipid IV
  • synthetic octasaccharide

ASJC Scopus subject areas

  • Molecular Medicine

Cite this

Hada, N., Sugita, M., Takeda, T., Maki, T., & Ogihara, Y. (1994). Inhibitory effect of anti-lipid IV antiserum binding activity of various synthetic oligosaccharides. Yakugaku Zasshi, 114(5), 333-341.

Inhibitory effect of anti-lipid IV antiserum binding activity of various synthetic oligosaccharides. / Hada, N.; Sugita, M.; Takeda, T.; Maki, T.; Ogihara, Y.

In: Yakugaku Zasshi, Vol. 114, No. 5, 1994, p. 333-341.

Research output: Contribution to journalArticle

Hada, N, Sugita, M, Takeda, T, Maki, T & Ogihara, Y 1994, 'Inhibitory effect of anti-lipid IV antiserum binding activity of various synthetic oligosaccharides', Yakugaku Zasshi, vol. 114, no. 5, pp. 333-341.
Hada, N. ; Sugita, M. ; Takeda, T. ; Maki, T. ; Ogihara, Y. / Inhibitory effect of anti-lipid IV antiserum binding activity of various synthetic oligosaccharides. In: Yakugaku Zasshi. 1994 ; Vol. 114, No. 5. pp. 333-341.
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