Initial predictors of development of pure red cell aplasia in myasthenia gravis after thymectomy

Shigeaki Suzuki, Shigeru Nogawa, Kortaro Tanaka, Atsuo Koto, Yasuo Fukuuchi, Masataka Kuwana

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Pure red cell aplasia (PRCA) is well known to be concomitant with myasthenia gravis (MG), but it is difficult to predict the development of PRCA in patients with MG. Of 135 patients with MG, four (2.9%) had PRCA. All patients developed PRCA after thymectomy during a period when MG was in remission. The frequencies of thymoma, bulbar involvement and high anti-acetylcholine receptor (AChR) antibody levels were significantly higher in four patients with PRCA. Japanese MG patients with these characteristics at presentation were at significant risk for the development of PRCA after thymectomy.

Original languageEnglish
Pages (from-to)16-18
Number of pages3
JournalClinical Neurology and Neurosurgery
Volume106
Issue number1
DOIs
Publication statusPublished - 2003 Dec

Keywords

  • HLA class II
  • Myasthenia gravis
  • Pure red cell aplasia
  • Thymectomy

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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