Inositol trisphosphate receptors in the vascular development

Keiko Uchida; Maki Nakazawa; Chihiro Yamagishi; Katsuhiko Mikoshiba; Hiroyuki Yamagishi

doi:10.1007/978-4-431-54628-3_32

Inositol trisphosphate receptors in the vascular development

Keiko Uchida, Maki Nakazawa, Chihiro Yamagishi, Katsuhiko Mikoshiba, Hiroyuki Yamagishi

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

The placental circulation is crucial for the development of mammalian embryos [1]. The labyrinth layer in the placenta is created by extensive villous branching of the trophoblast and vascularization arising from the embryonic mesoderm. In the labyrinth, materials are exchanged between the maternal and embryonic circulation. Recently, we have found that inositol 1,4,5-trisphosphate (IP₃) receptors (IP₃Rs) may be required for the placental vascularization.

Original language	English
Title of host publication	Etiology and Morphogenesis of Congenital Heart Disease
Subtitle of host publication	From Gene Function and Cellular Interaction to Morphology
Publisher	Springer Japan
Pages	237-239
Number of pages	3
ISBN (Electronic)	9784431546283
ISBN (Print)	9784431546276
DOIs	https://doi.org/10.1007/978-4-431-54628-3_32
Publication status	Published - 2016 Jan 1

Keywords

Angiogenesis
Intracellular calcium
Placenta
Vascular development

ASJC Scopus subject areas

Medicine(all)
Biochemistry, Genetics and Molecular Biology(all)

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10.1007/978-4-431-54628-3_32

Cite this

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abstract = "The placental circulation is crucial for the development of mammalian embryos [1]. The labyrinth layer in the placenta is created by extensive villous branching of the trophoblast and vascularization arising from the embryonic mesoderm. In the labyrinth, materials are exchanged between the maternal and embryonic circulation. Recently, we have found that inositol 1,4,5-trisphosphate (IP3) receptors (IP3Rs) may be required for the placental vascularization.",

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AU - Uchida, Keiko

AU - Nakazawa, Maki

AU - Yamagishi, Chihiro

AU - Mikoshiba, Katsuhiko

AU - Yamagishi, Hiroyuki

PY - 2016/1/1

Y1 - 2016/1/1

N2 - The placental circulation is crucial for the development of mammalian embryos [1]. The labyrinth layer in the placenta is created by extensive villous branching of the trophoblast and vascularization arising from the embryonic mesoderm. In the labyrinth, materials are exchanged between the maternal and embryonic circulation. Recently, we have found that inositol 1,4,5-trisphosphate (IP3) receptors (IP3Rs) may be required for the placental vascularization.

AB - The placental circulation is crucial for the development of mammalian embryos [1]. The labyrinth layer in the placenta is created by extensive villous branching of the trophoblast and vascularization arising from the embryonic mesoderm. In the labyrinth, materials are exchanged between the maternal and embryonic circulation. Recently, we have found that inositol 1,4,5-trisphosphate (IP3) receptors (IP3Rs) may be required for the placental vascularization.

KW - Angiogenesis

KW - Intracellular calcium

KW - Placenta

KW - Vascular development

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SP - 237

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BT - Etiology and Morphogenesis of Congenital Heart Disease

PB - Springer Japan

ER -

Inositol trisphosphate receptors in the vascular development

Abstract

Keywords

ASJC Scopus subject areas

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