To analyze the utility of insulin-like growth factor binding protein-3 (IGFBP-3) radioimmunoassay in the diagnosis of GH insufficiency (GHI) and compare the results of IGFBP-3 and IGF-1, we measured IGF-1 and IGFBP-3 in sera from normalchildren (n=309), short children (n =99) and patients with GHI (n=73). We divided the GHI group into two groups (complete and partial GHD) and divided all the patients into two groups depending upon age (less than and older than 10 years).
- growth hormone deficiency (GHD)
- I GF-1
- normal short children (NS)
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Endocrinology, Diabetes and Metabolism