Insulin resistance syndrome in adolescents and adults

Ikuo Saito, Hiroshi Kawabe, Eiko Takeshita, Hideki Wainai, Kazuko Murata, Takao Saruta

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

This study was designed to investigate the possibility of sex and age differences in the insulin-blood pressure relationship in a general Japanese population with a wide age range. Fasting serum insulin, lipids, plasma glucose, blood pressure and anthropometric measurements were made on 1,537 men and 843 women aged 16 to 65 years. Of the 2,380 subjects in the present analysis, 290 (184 men, 106 women) were hypertensive. When divided into four age groups (16 to 17, 21 to 22, 30 to 49 and 50 to 65 years), the male hypertensive subjects were found to have significantly higher fasting insulin levels, triglycerides levels and body mass index and lower glucose/insulin ratios than normotensive male subjects in all age groups. In the women, there was no significant difference in serum insulin levels or glucose insulin ratios between the hypertensive and normotensive groups in any age group. Simple correlation analysis showed that blood pressure was statistically significantly correlated with serum insulin levels and body mass index in the men in all age groups. In women, the correlation between blood pressure and serum insulin was insignificant in the 21- to 22-year-old age group. In men but not women, multivariate analysis showed that blood pressure was significantly and independently correlated with fasting serum insulin levels. The results of this study suggests the existence of sex and age differences in the insulin-blood pressure relationship in a Japanese population.

Original languageEnglish
JournalHypertension Research
Volume19
Issue numberSUPPL. 1
Publication statusPublished - 1996 Jun

Fingerprint

Insulin Resistance
Insulin
Blood Pressure
Age Groups
Fasting
Serum
Glucose
Sex Characteristics
Body Mass Index
Population
Triglycerides
Multivariate Analysis
Lipids

Keywords

  • Age
  • Hypertension
  • Insulin
  • Sex

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Saito, I., Kawabe, H., Takeshita, E., Wainai, H., Murata, K., & Saruta, T. (1996). Insulin resistance syndrome in adolescents and adults. Hypertension Research, 19(SUPPL. 1).

Insulin resistance syndrome in adolescents and adults. / Saito, Ikuo; Kawabe, Hiroshi; Takeshita, Eiko; Wainai, Hideki; Murata, Kazuko; Saruta, Takao.

In: Hypertension Research, Vol. 19, No. SUPPL. 1, 06.1996.

Research output: Contribution to journalArticle

Saito, I, Kawabe, H, Takeshita, E, Wainai, H, Murata, K & Saruta, T 1996, 'Insulin resistance syndrome in adolescents and adults', Hypertension Research, vol. 19, no. SUPPL. 1.
Saito I, Kawabe H, Takeshita E, Wainai H, Murata K, Saruta T. Insulin resistance syndrome in adolescents and adults. Hypertension Research. 1996 Jun;19(SUPPL. 1).
Saito, Ikuo ; Kawabe, Hiroshi ; Takeshita, Eiko ; Wainai, Hideki ; Murata, Kazuko ; Saruta, Takao. / Insulin resistance syndrome in adolescents and adults. In: Hypertension Research. 1996 ; Vol. 19, No. SUPPL. 1.
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